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Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
  1. Patrick J Owen1,
  2. Clint T Miller1,
  3. Niamh L Mundell1,
  4. Simone JJM Verswijveren1,
  5. Scott D Tagliaferri1,
  6. Helena Brisby2,
  7. Steven J Bowe3,
  8. Daniel L Belavy1
  1. 1Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia
  2. 2Department of Orthopaedics, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden
  3. 3Faculty of Health, Biostatistics Unit, Deakin University, Geelong, Victoria, Australia
  1. Correspondence to Associate Professor Daniel L Belavy, Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3125, Australia; belavy{at}gmail.com

Abstract

Objective Examine the effectiveness of specific modes of exercise training in non-specific chronic low back pain (NSCLBP).

Design Network meta-analysis (NMA).

Data sources MEDLINE, CINAHL, SPORTDiscus, EMBASE, CENTRAL.

Eligibility criteria Exercise training randomised controlled/clinical trials in adults with NSCLBP.

Results Among 9543 records, 89 studies (patients=5578) were eligible for qualitative synthesis and 70 (pain), 63 (physical function), 16 (mental health) and 4 (trunk muscle strength) for NMA. The NMA consistency model revealed that the following exercise training modalities had the highest probability (surface under the cumulative ranking (SUCRA)) of being best when compared with true control: Pilates for pain (SUCRA=100%; pooled standardised mean difference (95% CI): −1.86 (–2.54 to –1.19)), resistance (SUCRA=80%; −1.14 (–1.71 to –0.56)) and stabilisation/motor control (SUCRA=80%; −1.13 (–1.53 to –0.74)) for physical function and resistance (SUCRA=80%; −1.26 (–2.10 to –0.41)) and aerobic (SUCRA=80%; −1.18 (–2.20 to –0.15)) for mental health. True control was most likely (SUCRA≤10%) to be the worst treatment for all outcomes, followed by therapist hands-off control for pain (SUCRA=10%; 0.09 (–0.71 to 0.89)) and physical function (SUCRA=20%; −0.31 (–0.94 to 0.32)) and therapist hands-on control for mental health (SUCRA=20%; −0.31 (–1.31 to 0.70)). Stretching and McKenzie exercise effect sizes did not differ to true control for pain or function (p>0.095; SUCRA<40%). NMA was not possible for trunk muscle endurance or analgesic medication. The quality of the synthesised evidence was low according to Grading of Recommendations Assessment, Development and Evaluation criteria.

Summary/conclusion There is low quality evidence that Pilates, stabilisation/motor control, resistance training and aerobic exercise training are the most effective treatments, pending outcome of interest, for adults with NSCLBP. Exercise training may also be more effective than therapist hands-on treatment. Heterogeneity among studies and the fact that there are few studies with low risk of bias are both limitations.

  • physical activity
  • spine
  • rehabilitation
  • physical therapy modalities
  • behavioural symptoms
  • analgesics
  • catastrophization

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Footnotes

  • Twitter @PatrickOwenPhD, @_clintmiller, @NiamhMundell, @S1_Verswijveren, @ScottTags, @BelavySpine

  • Contributors Secured funding: CM, DB. Study conception: PO, CM, HB, DB. Screening: PO, NM, SV. Extraction: PO, NM, ST. Statistical analyses: SB, DB. Drafted manuscript: PO, DB. Approved final manuscript: All.

  • Funding This project was funded by Musculoskeletal Australia (formerly MOVE muscle, bone and joint health; CONTR2017/00399).

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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