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What did I do?
In this PhD project, we prospectively included 86 patients with knee osteoarthritis (OA) who were scheduled for a total knee arthroplasty (TKA). The project was divided into two phases: Phase 1, compared the relationship between lower limb sit-to-stand power (STS Power) and maximal isometric knee extensor strength (knee extensor maximal isometric voluntary contraction (MVC)), respectively, with objective measures of physical function and patient-reported outcomes. Phase 2, investigated the effectiveness of preoperative low-load blood flow restricted resistance training (BFR-RT) compared with usual preoperative medical care on postoperative measures of physical function, lower limb strength and patient-reported outcomes obtained 3 and 12 months after TKA.
Why did I do it?
The number of TKA procedures due to knee OA is rising globally, with ~20% of the patients perceiving insufficient postoperative outcomes. Moreover, patients undergoing TKA demonstrate a lower level of physical function 1 year postoperatively compared with healthy peers.1 Interestingly, performing preoperative heavy-load resistance strength training (HL-RT) to improve preoperative lower limb strength in patients with knee and hip OA scheduled for joint replacement surgery has demonstrated to enhance postoperative physical function.2 However, a previous study3 reported that about 25% …
Footnotes
Contributors SLJ is the sole contributor and guarantor of this manuscript.
Funding Aase og Ejnar Danielsens Fond, Augustinus Fonden, Christian og Ottilia Brorsons Rejselegat til unge videnskabsmænd- og kvinder, Danske Fysioterapeuter, Elisabeth & Karl Ejnar Nis Hanssens Mindeslegat, Familien Hede Nielsens Fond, Hartmann Fonden, Helga og Peter Kornings Fond, Sundhed, Region Midtjylland, William Demant Fonden.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.