RT Journal Article SR Electronic T1 Rest and treatment/rehabilitation following sport-related concussion: a systematic review JF British Journal of Sports Medicine JO Br J Sports Med FD BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine SP 930 OP 934 DO 10.1136/bjsports-2016-097475 VO 51 IS 12 A1 Schneider, Kathryn J A1 Leddy, John J A1 Guskiewicz, Kevin M A1 Seifert, Tad A1 McCrea, Michael A1 Silverberg, Noah D A1 Feddermann-Demont, Nina A1 Iverson, Grant L A1 Hayden, Alix A1 Makdissi, Michael YR 2017 UL http://bjsm.bmj.com/content/51/12/930.abstract AB Aim or objective The objective of this systematic review was to evaluate the evidence regarding rest and active treatment/rehabilitation following sport-related concussion (SRC).Design Systematic review.Data sources MEDLINE (OVID), CINAHL (EbscoHost), PsycInfo (OVID), Cochrane Central Register of Controlled Trials (OVID), SPORTDiscus (EbscoHost), EMBASE (OVID) and Proquest DissertationsandTheses Global (Proquest) were searched systematically.Eligibility criteria for selecting studies Studies were included if they met the following criteria: (1) original research; (2) reported SRC as the diagnosis; and (3) evaluated the effect of rest or active treatment/rehabilitation. Review articles were excluded.Results Twenty-eight studies met the inclusion criteria (9 regarding the effects of rest and 19 evaluating active treatment). The methodological quality of the literature was limited; only five randomised controlled trials (RCTs) met the eligibility criteria. Those RCTs included rest, cervical and vestibular rehabilitation, subsymptom threshold aerobic exercise and multifaceted collaborative care.Summary/conclusions A brief period (24–48 hours) of cognitive and physical rest is appropriate for most patients. Following this, patients should be encouraged to gradually increase activity. The exact amount and duration of rest are not yet well defined and require further investigation. The data support interventions including cervical and vestibular rehabilitation and multifaceted collaborative care. Closely monitored subsymptom threshold, submaximal exercise may be of benefit.Systematic review registration PROSPERO 2016:CRD42016039570