TY - JOUR T1 - Prenatal exercise for the prevention of gestational diabetes mellitus and hypertensive disorders of pregnancy: a systematic review and meta-analysis JF - British Journal of Sports Medicine JO - Br J Sports Med SP - 1367 LP - 1375 DO - 10.1136/bjsports-2018-099355 VL - 52 IS - 21 AU - Margie H Davenport AU - Stephanie-May Ruchat AU - Veronica J Poitras AU - Alejandra Jaramillo Garcia AU - Casey E Gray AU - Nick Barrowman AU - Rachel J Skow AU - Victoria L Meah AU - Laurel Riske AU - Frances Sobierajski AU - Marina James AU - Amariah J Kathol AU - Megan Nuspl AU - Andree-Anne Marchand AU - Taniya S Nagpal AU - Linda G Slater AU - Ashley Weeks AU - Kristi B Adamo AU - Gregory A Davies AU - Ruben Barakat AU - Michelle F Mottola Y1 - 2018/11/01 UR - http://bjsm.bmj.com/content/52/21/1367.abstract N2 - Objective Gestational diabetes mellitus (GDM), gestational hypertension (GH) and pre-eclampsia (PE) are associated with short and long-term health issues for mother and child; prevention of these complications is critically important. This study aimed to perform a systematic review and meta-analysis of the relationships between prenatal exercise and GDM, GH and PE.Design Systematic review with random effects meta-analysis and meta-regression.Data sources Online databases were searched up to 6 January 2017.Study eligibility criteria Studies of all designs were included (except case studies) if published in English, Spanish or French, and contained information on the Population (pregnant women without contraindication to exercise), Intervention (subjective or objective measures of frequency, intensity, duration, volume or type of exercise, alone [“exercise-only”] or in combination with other intervention components [e.g., dietary; “exercise + co-intervention”]), Comparator (no exercise or different frequency, intensity, duration, volume and type of exercise) and Outcomes (GDM, GH, PE).Results A total of 106 studies (n=273 182) were included. ‘Moderate’ to ‘high’-quality evidence from randomised controlled trials revealed that exercise-only interventions, but not exercise+cointerventions, reduced odds of GDM (n=6934; OR 0.62, 95% CI 0.52 to 0.75), GH (n=5316; OR 0.61, 95% CI 0.43 to 0.85) and PE (n=3322; OR 0.59, 95% CI 0.37 to 0.9) compared with no exercise. To achieve at least a 25% reduction in the odds of developing GDM, PE and GH, pregnant women need to accumulate at least 600 MET-min/week of moderate-intensity exercise (eg, 140 min of brisk walking, water aerobics, stationary cycling or resistance training).Summary/conclusions In conclusion, exercise-only interventions were effective at lowering the odds of developing GDM, GH and PE. ER -