@article {Breda501, author = {Stephan J Breda and Edwin H G Oei and Johannes Zwerver and Edwin Visser and Erwin Waarsing and Gabriel P Krestin and Robert-Jan de Vos}, title = {Effectiveness of progressive tendon-loading exercise therapy in patients with patellar tendinopathy: a randomised clinical trial}, volume = {55}, number = {9}, pages = {501--509}, year = {2021}, doi = {10.1136/bjsports-2020-103403}, publisher = {British Association of Sport and Excercise Medicine}, abstract = {Objective To compare the effectiveness of progressive tendon-loading exercises (PTLE) with eccentric exercise therapy (EET) in patients with patellar tendinopathy (PT).Methods In a stratified, investigator-blinded, block-randomised trial, 76 patients with clinically diagnosed and ultrasound-confirmed PT were randomly assigned in a 1:1 ratio to receive either PTLE or EET. The primary end point was clinical outcome after 24 weeks following an intention-to-treat analysis, as assessed with the validated Victorian Institute of Sports Assessment for patellar tendons (VISA-P) questionnaire measuring pain, function and ability to play sports. Secondary outcomes included the return to sports rate, subjective patient satisfaction and exercise adherence.Results Patients were randomised between January 2017 and July 2019. The intention-to-treat population (mean age, 24 years, SD 4); 58 (76\%) male) consisted of patients with mostly chronic PT (median symptom duration 2 years). Most patients (82\%) underwent prior treatment for PT but failed to recover fully. 38 patients were randomised to the PTLE group and 38 patients to the EET group. The improvement in VISA-P score was significantly better for PTLE than for EET after 24 weeks (28 vs 18 points, adjusted mean between-group difference, 9 (95\% CI 1 to 16); p=0.023). There was a trend towards a higher return to sports rate in the PTLE group (43\% vs 27\%, p=0.13). No significant between-group difference was found for subjective patient satisfaction (81\% vs 83\%, p=0.54) and exercise adherence between the PTLE group and EET group after 24 weeks (40\% vs 49\%, p=0.33).Conclusions In patients with PT, PTLE resulted in a significantly better clinical outcome after 24 weeks than EET. PTLE are superior to EET and are therefore recommended as initial conservative treatment for PT.Data are available on reasonable request. The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.}, issn = {0306-3674}, URL = {https://bjsm.bmj.com/content/55/9/501}, eprint = {https://bjsm.bmj.com/content/55/9/501.full.pdf}, journal = {British Journal of Sports Medicine} }