RT Journal Article
SR Electronic
T1 Variable schedules of ibuprofen for ankle sprains.
JF British Journal of Sports Medicine
JO Br J Sports Med
FD BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
SP 203
OP 206
DO 10.1136/bjsm.19.4.203
VO 19
IS 4
A1 G R McLatchie
A1 C Allister
A1 C MacEwen
A1 G Hamilton
A1 H McGregor
A1 I Colquhuon
A1 N J Pickvance
YR 1985
UL http://bjsm.bmj.com/content/19/4/203.abstract
AB In a study of 144 patients, with Grade 1 and 2 inversion injuries to the ankle sustained in sport, treatment with a non-steroidal anti-inflammatory was considerably superior to placebo with respect to joint tenderness, level of training and injury severity. No difference in efficacy could be determined between ibuprofen 2400 mg given in two or four equally divided daily doses. Ten patients withdrew from the study because of side effects, five from ibuprofen twice daily, three from ibuprofen four times daily and two from the placebo group. This study confirms the efficacy, flexibility and tolerability of high dose ibuprofen.