TY - JOUR T1 - Understanding tendinopathies JF - British Journal of Sports Medicine JO - Br J Sports Med SP - 279 LP - 279 DO - 10.1136/bjsm.37.3.279 VL - 37 IS - 3 AU - A Scott AU - V Duronio Y1 - 2003/06/01 UR - http://bjsm.bmj.com/content/37/3/279.1.abstract N2 - We commend Professor Murrell for making a major novel contribution to the understanding, and thus potentially the treatment, of chronic tendinopathies.1 He has shown in patients with supraspinatus tendinopathy that a substantial portion of the cellular compartment of the tendon shows nuclear fragmentation, a key characteristic of apoptosis.2Does Professor Murrell feel that apoptosis would necessarily be a “harmful” pathological event in tendon or might there be an optimal, basal level of apoptosis? We appreciate that excessive apoptosis—programmed cell death—is a feature of degenerative … ER -