PT  - JOURNAL ARTICLE
AU  - M Ramírez
AU  - A Lucia
AU  - F Gómez-Gallego
AU  - J Esteve-Lanao
AU  - A Pérez-Martínez
AU  - C Foster
AU  - A L Andreu
AU  - M A Martin
AU  - L Madero
AU  - J Arenas
AU  - J García-Castro
TI  - Mobilisation of mesenchymal cells into blood in response to skeletal muscle injury
AID  - 10.1136/bjsm.2006.028639
DP  - 2006 Aug 01
TA  - British Journal of Sports Medicine
PG  - 719--722
VI  - 40
IP  - 8
4099  - http://bjsm.bmj.com/content/40/8/719.short
4100  - http://bjsm.bmj.com/content/40/8/719.full
SO  - Br J Sports Med2006 Aug 01; 40
AB  - Mesenchymal cells recruited to damaged tissues must circulate through the bloodstream. The absolute numbers of circulating mesenchymal stem cells (cMSCs) in two different models of acute and chronic skeletal muscle injury were determined. cMSCs were present in significantly higher numbers in both models than in healthy controls. These results support the hypothesis that MSCs are mobilised into the bloodstream after skeletal muscle tissue damage. These two models (acute and chronic) would be of value in the search for molecular mediators of mobilisation of MSCs into the circulation.