TY - JOUR T1 - Echocardiographic deformation imaging reveals preserved regional systolic function in endurance athletes with left ventricular hypertrophy JF - British Journal of Sports Medicine JO - Br J Sports Med SP - 872 LP - 878 DO - 10.1136/bjsm.2008.054346 VL - 44 IS - 12 AU - A J Teske AU - N H Prakken AU - B W De Boeck AU - B K Velthuis AU - P A Doevendans AU - M J Cramer Y1 - 2010/09/01 UR - http://bjsm.bmj.com/content/44/12/872.abstract N2 - Background Left ventricular hypertrophy (LVH) is often observed in athletes, which should be differentiated from hypertrophic cardiomyopathy. The aim of the study was to explore the functional changes measured using tissue Doppler imaging (TDI) deformation analysis in athletes fulfilling LVH criteria participating in different endurance sports. Methods Healthy controls (n = 62, 58% men) and endurance athletes (n = 120, 62% men) aged 18–40 years were prospectively enrolled and underwent both standard echocardiography as well as TDI. Longitudinal TDI-derived strain and strain rate (SR) were calculated in the septal and posterior wall in three segments. LVH was defined as a left ventricular mass (LVM) over 132 g/m2 in men and over 109 g/m2 in women. Results Echocardiographic LVH was observed in 33 athletes (67% men). LVM was significantly increased in both athlete groups (102.6 g/m2 (SD 16.0) and 135.7 g/m2 (SD 15.9) vs 88.0 g/m2 (SD 16.5) in controls, p<0.001). Diastolic parameters were not significantly different between groups. Athletes with LVH showed no significant difference in strain and SR values in any segment of the septal or posterior wall compared with controls or those without LVH. A weak but significant correlation (also after multivariate analysis) was found for septal wall thickness and LVM in peak systolic strain (r = 0.26, p<0.01 and 0.23, p<0.01) and SR (r = 0.27, p<0.01 and 0.29, p<0.01). Nevertheless, strain and SR values were still within normal limits in all athletes. Conclusion Athletes with LVH overall show normal deformation values in the left ventricle. These data suggest that a moderate reduction in regional septal deformation should not be considered as pathological when evaluating the endurance athlete with echocardiographic LVH of unknown origin. ER -