RT Journal Article SR Electronic T1 Optimising ankle sprain prevention: a critical review and practical appraisal of the literature JF British Journal of Sports Medicine JO Br J Sports Med FD BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine SP 1082 OP 1088 DO 10.1136/bjsm.2010.076406 VO 44 IS 15 A1 E A L M Verhagen A1 K Bay YR 2010 UL http://bjsm.bmj.com/content/44/15/1082.abstract AB Objectives To establish the effect of preventive measures and assert the optimal prevention strategy for acute lateral ligament injury to the ankle. Methods An electronic literature search was employed to look for published randomised controlled trials, a controlled trials or time interventions containing research questions regarding the prevention of lateral ankle ligament injuries. Two reviewers reviewed relevant studies for strengths and weaknesses in design and methodology, according to a standardised set of predefined criteria. A total of 24 relevant studies met the criteria for inclusion and were analysed. Results Overall taping, bracing and neuromuscular training were all effective for the prevention of ankle-sprain recurrences. The RRs of these prophylactic measures are of similar magnitude, ranging from 0.2 to 0.5 when compared with control groups. Although preventive effects have been reported in a general athletic population, evidence suggests this overall effect is due to a strong preventive effect in previously injured athletes and that any effect on fresh ankle sprains is either non-existent or very low. Conclusions Based on these outcomes, a combination of an external prophylactic measure (tape or brace) with neuromuscular training will achieve the best preventive outcomes with minimal burden for the athlete.