PT - JOURNAL ARTICLE AU - G Galanti AU - L Stefani AU - L Toncelli AU - M C R Vono AU - R Mercuri AU - N Maffulli TI - Effects of sports activity in athletes with bicuspid aortic valve and mild aortic regurgitation AID - 10.1136/bjsm.2008.047407 DP - 2010 Mar 01 TA - British Journal of Sports Medicine PG - 275--279 VI - 44 IP - 4 4099 - http://bjsm.bmj.com/content/44/4/275.short 4100 - http://bjsm.bmj.com/content/44/4/275.full SO - Br J Sports Med2010 Mar 01; 44 AB - Objective In this study, the impact of regular training on left ventricle morphology in a group of athletes with bicuspid aortic valve (BAV) was evaluated. Design Longitudinal cohort study. A group of competitive athletes with BAV was followed up with a yearly standard echocardiographic examination for 5 years. Setting Sport Medicine Centre, University of Florence, Pre-Participation Protocol Study Participants A group of 88 consecutive athletes diagnosed with BAV was identified in the period January to December 1999, and 30 of these completed a 5-year follow-up. They were compared with a group of 56 athletes with a normal tricuspid valve (TAV). Results BAV athletes showed significant progressive increase in left ventricular dimensions and aortic diameters at four levels. The values were within the range of the general and non-athletic BAV populations. In TAV athletes, the aortic and left ventricle dimensions did not increase significantly and remained within physiological range. Conclusions Left ventricular dimensions in competitive BAV athletes remain within the normal range. There is, however, a significant progressive increase in the BAV group compared with the TAV group. These results are in agreement with data obtained in previous studies on the non-athletic BAV population. Sports activity does not have an additional effect on cardiac morphology in athletes with asymptomatic BAV associated with mild regurgitation, for at least 5 years.