TY - JOUR T1 - Respiratory health of elite athletes – preventing airway injury: a critical review JF - British Journal of Sports Medicine JO - Br J Sports Med SP - 471 LP - 476 DO - 10.1136/bjsports-2012-091056 VL - 46 IS - 7 AU - Pascale Kippelen AU - Kenneth D Fitch AU - Sandra Doreen Anderson AU - Valerie Bougault AU - Louis-Philippe Boulet AU - Kenneth William Rundell AU - Malcolm Sue-Chu AU - Donald C McKenzie Y1 - 2012/06/01 UR - http://bjsm.bmj.com/content/46/7/471.abstract N2 - Elite athletes, particularly those engaged in endurance sports and those exposed chronically to airborne pollutants/irritants or allergens, are at increased risk for upper and lower airway dysfunction. Airway epithelial injury may be caused by dehydration and physical stress applied to the airways during severe exercise hyperpnoea and/or by inhalation of noxious agents. This is thought to initiate an inflammatory cascade/repair process that, ultimately, could lead to airway hyperresponsiveness (AHR) and asthma in susceptible athletes. The authors review the evidence relating to prevention or reduction of the risk of AHR/asthma development. Appropriate measures should be implemented when athletes exercise strenuously in an attempt to attenuate the dehydration stress and reduce the exposure to noxious airborne agents. Environmental interventions are the most important. Non-pharmacological strategies can assist, but currently, pharmacological measures have not been demonstrated to be effective. Whether early prevention of airway injury in elite athletes can prevent or reduce progression to AHR/asthma remains to be established. ER -