PT  - JOURNAL ARTICLE
AU  - Kassia S Weston
AU  - Ulrik Wisløff
AU  - Jeff S Coombes
TI  - High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis
AID  - 10.1136/bjsports-2013-092576
DP  - 2014 Aug 01
TA  - British Journal of Sports Medicine
PG  - 1227--1234
VI  - 48
IP  - 16
4099  - http://bjsm.bmj.com/content/48/16/1227.short
4100  - http://bjsm.bmj.com/content/48/16/1227.full
SO  - Br J Sports Med2014 Aug 01; 48
AB  - Background/Aim Cardiorespiratory fitness (CRF) is a strong determinant of morbidity and mortality. In athletes and the general population, it is established that high-intensity interval training (HIIT) is superior to moderate-intensity continuous training (MICT) in improving CRF. This is a systematic review and meta-analysis to quantify the efficacy and safety of HIIT compared to MICT in individuals with chronic cardiometabolic lifestyle diseases. Methods The included studies were required to have a population sample of chronic disease, where poor lifestyle is considered as a main contributor to the disease. The procedural quality of the studies was assessed by use of a modified Physiotherapy Evidence Base Database (PEDro) scale. A meta-analysis compared the mean difference (MD) of preintervention versus postintervention CRF (VO2peak) between HIIT and MICT. Results 10 studies with 273 patients were included in the meta-analysis. Participants had coronary artery disease, heart failure, hypertension, metabolic syndrome and obesity. There was a significantly higher increase in the VO2peak after HIIT compared to MICT (MD 3.03 mL/kg/min, 95% CI 2.00 to 4.07), equivalent to 9.1%. Conclusions HIIT significantly increases CRF by almost double that of MICT in patients with lifestyle-induced chronic diseases.