Table 1

Characteristics of case–control studies included

AuthorSexAge (years)Case sample (N)Case BMI (kg/m2)Control sample (N)Control BMI (kg/m2)
Adolescents with PFP
 Patil et al25Mixed15.8±2.52020.9±1.91722.1±3.3
 Rathleff et al26Female17.2 (17–18)5720.0±1.92920.8±3.3
Adults with PFP
 Aminaka et al27Mixed20.3±1.92024.8±3.62024.0±2.5
 Baldon et al28Females22.9±5.21022.4±3.61021.2±2.5
 Bazett-Jones et al29Mixed26.0±5.51922.3±3.61923.2±2.5
 Besier et al30Females28.8±4.71622.2±3.6821.2±2.5
Males27.2±3.01122.9±3.6823.2±2.5
 Boling et al31Mixed24.0±6.01425.4±3.61424.8±2.5
 Callaghan et al32Mixed34.4±11.55726.0±5.21023.6±3.2
 Caylor et al33Mixed23.0±NR5023.5±3.62022.4±2.5
 Chiu et al34Mixed34.3±9.8923.1±3.6621.1±2.5
 Crossley et al35Mixed28.0±8.04823.9±4.01822.2±2.7
 Dierks et al36Mixed24.1±7.42022.5±3.62021.8±2.5
 Draper et al37Females28.0±5.02222.0±3.6818.1±2.5
Males30.0±4.01223.4±3.6822.7±2.5
 Duffey et al38Mixed36.0±1.09923.3±3.07022.9±2.5
 Ferber et al39Mixed35.2±12.21525.4±3.61024.4±2.5
 Jensen et al40Mixed31.2±NR9125.8±5.52323.4±2.0
 Joensen et al41Mixed22.3±NR2423.0±1.91722.2±2.5
 Laprade et al42Mixed30.8±8.53325.4±3.63323.9±2.5
 Livingston et al43Females25.7±2.51422.7±3.62424.0±2.5
Males28.9±2.91126.1±3.62625.6±2.5
 McClinton et al44Mixed29.5±102025.4±3.62026.6±2.5
 McMoreland et al45Females23.0 (19.0–31.0)1222.8±3.61223.0±2.5
 Nakagawa et al46Females22.3±3.12022.2±3.62022.4±2.5
Males24.2±4.42023.8±3.62024.1±2.5
 Naslund et al47Females30.0±9.01323.0±2.01824.0±2.0
Males37.0±12.0925.0±4.01827.0±3.0
 Ott et al48Mixed20.9±1.32024.1±3.62023.2±2.5
 Owings et al49Females33.7±6.91225.1±3.6425.6±2.5
Males29.1±10.7828.8±3.61023.4±2.5
 Piva et al50Mixed25.8±6.03026.6±3.63023.5±2.5
 Powers et al51Females25.6±7.12623.5±3.61921.7±2.5
 Saad et al52Females23.2±2.31522.9±3.61520.9±2.5
 Sacco et al53Mixed30.8±8.8623.0±3.2524.6±2.8
 Souza et al54Females27.0±6.01922.7±3.61922.3±2.5
 Stefanyshyn et al55Mixed34.6±9.82023.1±3.62022.6±2.5
 Thomee et al56Females20.3±3.04022.4±3.62021.6±2.5
 Tuncyurek et al57Mixed36.8±14.02325.7±4.3921.8±4.0
 Willson et al58Females23.3±3.12022.3±3.62022.2±2.5
 Wilson et al59Mixed30.2±12.5924.4±3.61022.7±2.5
Adults with PFOA
 Crossley et al60Mixed58.0±10.06027.5±3.73324.1±3.4
 Farrokhi et al61Mixed64.7±3.013431.9±6.73328.1±4.2
 Hoglund et al62Mixed52.0±7.5827.5±3.7724.1±3.4
 Pohl et al63Mixed55.0±9.01526.4±3.71525.0±3.5
  • Some studies reported data for males and females separately. Besier et al had two groups—females and males. Draper, Livingston, Nakagawa, Naslund, Owings all had two groups. Data are reported as mean±SD or mean (range).

  • BMI, body mass index; NR, not reported.