Groups of specific cancers—mortality and cardiorespiratory fitness (estimated VO2max) in the Copenhagen Male Study
| Estimated VO2max | No. subjects | No. cancer deaths | Crude HR (95% CI) | p Value | Adjusted HR* (95% CI) | p Value |
|---|---|---|---|---|---|---|
| Oral and digestive cancers†, VO2max,per 10 mL/kg/min increase | 5131 | 431 | 0.78 (0.67 to 0.88) | <0.001 | 0.86 (0.74 to 1.0) | 0.06 |
| Respiratory and thoracic cancers‡ VO2max per 10 mL/kg/min increase | 5131 | 471 | 0.72 (0.63 to 0.82) | <0.001 | 0.75 (0.65 to 0.87) | <0.001 |
| Male and urinary organs cancers§ VO2max per 10 mL/kg/min increase | 5131 | 373 | 0.80 (0.69 to 0.92) | 0.002 | 0.91 (0.77 to 1.06) | 0.23 |
| Other cancers¶ VO2max per 10 mL/kg/min increase | 5131 | 302 | 0.77 (0.66 to 0.91) | 0.002 | 0.80 (0.67 to 0.96) | 0.016 |
*Adjusted for age, smoking, grams of tobacco per day, systolic and diastolic blood pressure, previous myocardial infarction, diabetes, self-reported physical activity, alcohol and social class.
†ICD-8: 140–159; ICD-10: C00-C26.
‡ICD-8: 160–163, ICD-10: C30–39.
§ICD-8: 185–189; ICD-10: C60-C68.
¶ICD-8: 170–184, 190–209; ICD-10: C40–41, C43–58, C69–96.