Table 1

Results of moderator analysis

ModeratorNo. of effect sizesEstimate Mean (95% CI)Q statisticOmnibus test of moderators
Exercise moderators
ModeQ328=781.68; p<0.01Q5=39.53; p<0.01
 Aerobic1530.24 (0.10 to 0.37)
 Resistance training800.29 (0.13 to 0.44)
 Multicomponent training470.33 (0.14 to 0.53)
 Tai chi250.52 (0.32 to 0.71)
 Yoga280.13 (−0.10 to 0.36)
DurationQ318=789.68; p<0.01Q3=27.83; p<0.01
 Short (≤45 min)360.09 (−0.28 to 0.46)
 Medium (>45 to ≤60 min)2630.31 (0.16 to 0.46)
 Long (>60 min)240.33 (−0.04 to 0.65)
FrequencyQ329=804.58; p<0.01Q3=24.12; p<0.01
 Low (≤2)920.32 (0.13 to 0.52)
 Medium (3–4)2290.24 (0.07 to 0.40)
 High (5-–7)130.69 (0.10 to 1.28)
IntensityQ207=264.61; p<0.01Q3=13.55; p<0.01
 Low710.10 (−0.02 to 0.23)
 Moderate570.17 (0.03 to 0.33)
 High830.16 (0.04 to 0.27)
LengthQ330=807.48 P<0.01Q3=23.32; p<0.01
 Short (4–12 weeks)780.31 (0.09 to 0.54)
 Medium (13–26 weeks)1700.28 (0.10 to 0.47)
 Long (>26 weeks)860.27 (0.03 to 0.52)
Cognitive moderators
Cognitive domainQ303=795.06; p<0.01Q5=28.08; p<0.01
 Global cognition60.16 (−0.14 to 0.47)
 Attention870.27 (0.14 to 0.41)
 Executive function940.34 (0.20 to 0.47)
 Memory810.36 (0.22 to 0.50)
 Working memory360.29 (0.12 to 0.45)
Study design moderators
Control groupQ328=785.37; p<0.01Q4=25.52; p<0.01
 Active1200.13 (−0.06 to 0.32)
 Education170.48 (0.14 to 0.82)
 No contact1890.34 (0.17 to 0.51)
 Social70.20 (−0.58 to 0.98)
Cognitive statusQ330=797.56; p<0.01Q3=21.62; p<0.01
 MCI - Yes1970.28 (0.11 to 0.44)
 MCI - No410.36 (0.04 to 0.68)
 Unclear960.28 (0.05 to 0.51)
  • MCI, mild cognitive impairment.