Association between number of sedentary breaks per hour* with all-cause mortality among 1181 British men without pre-existing CHD, stroke or heart failure
| Quartile 1 (0.3–5.7) | Quartile 2 (5.8–6.9) | Quartile 3 (7.0–8.4) | Quartile 4 (8.5–15.9) | Total | ||||
| Number of participants (n deaths) | 275 (64) | 305 (64) | 297 (38) | 304 (28) | 1181 (194) | |||
| Person-years | 1243 | 1428 | 1472 | 1504 | 5646 | |||
| Mortality/1000 person-years | 51.5 | 44.8 | 25.8 | 18.6 | 34.4 | |||
| HR† | 95% CI | HR† | 95% CI | HR† | 95% CI | |||
| Model 1‡ | Reference | 1.28 | 0.86 to 1.92 | 1.04 | 0.61 to 1.76 | 1.22 | 0.61 to 2.42 | |
| Model 2§ | Reference | 1.21 | 0.81 to 1.81 | 0.95 | 0.56 to 1.62 | 1.06 | 0.53 to 2.11 | |
| Model 3¶ | Reference | 1.22 | 0.81 to 1.82 | 0.95 | 0.56 to 1.61 | 1.01 | 0.50 to 2.02 | |
*A sedentary break is the interruption of a sedentary bout lasting >1 min by ≥1 min of LIPA or MVPA.
†HR is per quartile of sedentary breaks per hour.
‡Model 1=age+ region of residence+season of wear+accelerometer wear time+minutes of sedentary behaviour.
§Model 2=model 1+social class+alcohol use+smoking+sleep time+living alone+body mass index.
¶Model 3=model 2+mobility disability.
CHD, coronary heart disease; LIPA, light physical activity; MVPA, moderate to vigorous physical activity.