Table 2

Patellofemoral cartilage thickness changes over the total (0–5 years), early (0–2 years) and late (2–5 years) follow-up periods: total cohort and as-randomised*

Outcome (µm)Total cohortAs-randomised
Early ACLROptional delayed ACLRP value
Change in cartilage thickness between baseline and 5-year follow-up
 Participants included in analysisn=112n=59n=53
 Patella−11 (−36 to 14)−36 (−78 to, 5)18 (−7 to 42)0.022
 Trochlea−47 (−73 to –20)−72 (−118 to –26)−19 (−43 to 5)0.058
 Total patellofemoral joint−58 (−104 to –11)−108 (−189 to –27)−1 (−40 to 37)0.021
Change in cartilage thickness between baseline and 2 year follow-up
 Participants included in analysisn=112n=58n=54
 Patella−7 (−23 to 10)−25 (−52 to 1)14 (−6 to 34)0.018
 Trochlea−45 (−66 to –24)−63 (−100 to –26)−26 (−467 to –5)0.074
 Total patellofemoral joint−52 (−85 to –18)−88 (−145 to –31)−12 (−44 to 20)0.020
Change in cartilage thickness between 2 year and 5 year follow-up
 Participants included in analysisn=107n=58n=49
 Patella−4 (−22 to 15)−13 (−39 to 13)7 (−19 to 33)0.306
 Trochlea−1 (−16 to 14)−9 (−30 to 12)8 (−12 to 29)0.265
 Total patellofemoral joint−5 (−34 to 24)−22 (−64 to 20)15 (−24 to 55)0.227
  • P values calculated from linear mixed effects model (ie, the interaction between fixed-effects of group and follow-up periods, adjusted for age and sex).

  • *Changes in cartilage thickness (µm) are mean and 95% CI.

  • ACLR, anterior cruciate ligament reconstruction.