Table 2

Association between total leisure time physical activity level and risk of all-cause and cause-specific mortality

Leisure time PA level, minutes/week, HR (95% CI)
010 –5960–149150–299300–449450–799800– 1499≥1500
Participants (N)36 702369511 73911 5808280844651982500
All-cause
 Deaths (n)4687269871727479381300141
 Model 110.76 (0.66 to 0.87)0.69 (0.63 to 0.76)0.59 (0.54 to 0.65)0.58 (0.53 to 0.64)0.49 (0.44 to 0.55)0.56 (0.49 to 0.64)0.50 (0.42 to 0.59)
 Model 210.80 (0.70 to 0.93)0.75 (0.69 to 0.82)0.66 (0.60 to 0.72)0.65 (0.58 to 0.72)0.56 (0.50 to 0.63)0.62 (0.54 to 0.70)0.53 (0.45 to 0.64)
 Model 310.82 (0.72 to 0.95)0.78 (0.72 to 0.86)0.69 (0.63 to 0.75)0.67 (0.61 to 0.74)0.58 (0.52 to 0.66)0.63 (0.56 to 0.72)0.54 (0.45 to 0.64)
CVD
 Deaths (n)10386017513794807833
 Model 110.82 (0.62 to 1.08)0.66 (0.54 to 0.79)0.53 (0.43 to 0.64)0.53 (0.41 to 0.68)0.51 (0.39 to 0.66)0.63 (0.48 to 0.81)0.60 (0.40 to 0.88)
 Model 210.87 (0.66 to 1.15)0.73 (0.60 to 0.88)0.59 (0.49 to 0.73)0.60 (0.47 to 0.77)0.60 (0.46 to 0.78)0.70 (0.54 to 0.91)0.65 (0.44 to 0.96)
 Model 310.88 (0.67 to 1.17)0.76 (0.63 to 0.92)0.63 (0.52 to 0.78)0.64 (0.49 to 0.82)0.64 (0.49 to 0.83)0.74 (0.57 to 0.97)0.67 (0.45 to 0.99)
Cancer
 Deaths (n)12108026623617315510049
 Model 110.79 (0.61 to 1.02)0.73 (0.63 to 0.86)0.64 (0.54 to 0.75)0.73 (0.61 to 0.87)0.59 (0.49 to 0.71)0.58 (0.45 to 0.74)0.50 (0.36 to 0.69)
 Model 210.84 (0.65 to 1.09)0.80 (0.68 to 0.94)0.71 (0.60 to 0.84)0.82 (0.68 to 0.98)0.67 (0.56 to 0.81)0.64 (0.50 to 0.82)0.54 (0.39 to 0.74)
 Model 310.86 (0.66 to 1.11)0.84 (0.72 to 0.98)0.76 (0.64 to 0.89)0.85 (0.71 to 0.99)0.71 (0.59 to 0.86)0.65 (0.51 to 0.83)0.53 (0.39 to 0.73)

  • CI, confidence interval; CVD, cardiovascular disease; HR, hazards ratio.

  • Model 1: adjusted for sex, age and race/ethnicity.

  • Model 2: Model 1 plus additionally adjusted for education and marital status.

  • Model 3: Model 2 plus additionally adjusted for body mass index, smoking and alcohol intake.