Subgroup analyses for the effect of multifactorial intervention on rate of falls and risk of sustaining one or more falls and recurrent falls
| Subgroup analysis | Overall | ||||
| Trials, n | Participants, n | Effect estimate (random effects) 95% CI | I2 (%) | ||
|   | Rate of falls | ||||
| Selected at low versus high risk of falls | High risk | 14 | 5467 | 0.80 (0.69 to 0.93) | 92 |
| Any | 6 | 4649 | 0.75 (0.62 to 0.92) | 81 | |
| Included NICE-recommended components versus not included | 2+ | 17 | 6251 | 0.82 (0.72 to 0.94) | 91 |
| <2 | 3 | 3865 | 0.63 (0.46 to 0.87) | 92 | |
| Actively provided treatment to address fall-related risk factors versus referral | Active | 14 | 7307 | 0.79 (0.68 to 0.92) | 92 |
| Referral | 6 | 2809 | 0.77 (0.67 to 0.89) | 90 | |
| Usual care plus advice* versus usual care comparator | UC* | 5 | 4788 | 0.90 (0.78 to 1.03) | 81 |
| UC | 15 | 5328 | 0.75 (0.65 to 0.86) | 90 | |
|   | Risk of sustaining one or more falls | ||||
| Selected at low versus high risk of falls | High risk | 19 | 6843 | 0.96 (0.90 to 1.03) | 57 |
| Any | 11 | 6974 | 0.92 (0.82 to 1.02) | 53 | |
| Included NICE-recommended components versus not included | 2+ | 25 | 9614 | 0.96 (0.90 to 1.02) | 61 |
| <2 | 5 | 4270 | 0.90 (0.84 to 0.96) | 0 | |
| Actively provided treatment to address fall-related risk factors versus referral | Active | 17 | 8386 | 0.93 (0.88 to 0.99) | 48 |
| Referral | 13 | 5431 | 0.98 (0.87 to 1.10) | 68 | |
| Usual care plus advice* versus usual care comparator | UC* | 5 | 4902 | 0.94 (0.86 to 1.02) | 29 |
| UC | 25 | 8982 | 0.95 (0.89 to 1.02) | 59 | |
|   | Risk of sustaining recurrent falls | ||||
| Selected at low versus high risk of falls | High risk | 10 | 2825 | 0.93 (0.78 to 1.11) | 52 |
| Any | 5 | 4452 | 0.81 (0.72 to 0.91) | 0 | |
| Included NICE-recommended components versus not included | 2+ | 13 | 3642 | 0.88 (0.76 to 1.03) | 50 |
| <2 | 2 | 3635 | 0.85 (0.72 to 0.99) | 20 | |
| Actively provided treatment to address fall-related risk factors versus referral | Active | 10 | 6100 | 0.85 (0.74 to 0.98) | 44 |
| Referral | 5 | 1177 | 0.96 (0.74 to 1.23) | 41 | |
| Usual care plus advice* versus usual care comparator | UC* | 3 | 3909 | 0.86 (0.75 to 0.97) | 1 |
| UC | 12 | 3368 | 0.87 (0.74 to 1.03) | 46 | |
*Usual care and usual care plus non-tailored falls prevention advice in either written, audio or visual material format.
NICE, National Institute for Health and Care Excellence; UC, usual care.