Table 5

Effect of gender affirming hormones on athletic performance among transmen

Push-ups in 1 minMean (95% CI)Mean difference transmen vs CW (95% CI)Mean difference transmen vs CM (95% CI)
Time on hormones
 Pretreatment37.4 (33.2 to 41.5)4.8 (0.7 to 9.0)−16.1 (−20.3 to −12.0)
 0–1 years44.8 (40.5 to 49.0)12.2 (8.1 to 16.4)−8.7 (−12.9 to −4.6)
 1–2 years51.8 (46.2 to 57.5)19.3 (13.8 to 24.8)−1.7 (−7.2 to 3.9)
 2–2.5 years56.1 (49.9 to 62.4)25.6 (19.4 to 31.8)4.6 (−6.4 to 10.5)
β (95% CI)
Change in push-ups per month on hormones*0.46 (0.22 to 0.70)
Sit-ups in 1 min Mean (95% CI)
Time on hormones
 Pretreatment50.4 (47.4 to 53.4)4.8 (1.8 to 7.7)−2.0 (−4.9 to 0.9)
 0–1 years52.8 (49.8 to 55.8)7.2 (4.2 to 10.2)0.4 (−2.6 to 3.4)
 1–2 years58.2 (54.0 to 62.3)12.5 (8.5 to 16.6)5.7 (1.7 to 9.8)
 2–2.5 years58.3 (53.8 to 62.8)12.7 (8.2 to 17.1)5.9 (1.4 to 10.3)
β (95% CI)
Change in sit-ups per month on hormones*0.32 (0.16 to 0.49)
1.5 mile run time (s) Mean (95% CI)
Time on hormones
 Pretreatment850 (802 to 899)−4 (−52 to 43)131 (83 to 178)
 0–1 years826 (776 to 876)−29 (−78 to 20)106 (57 to 155)
 1–2 years751 (687 to 815)−104 (−167 to −41)31 (-32 to 94)
 2–2.5 years711 (640 to 783)−144 (−214 to −74)−9 (−79 to 61)
β (95% CI)
Change in run time per month on hormones*−3.2 (−5.3 to −1.2)
  • All analyses adjusted for variation in the number of measurements per research participant.

  • CW, average performance on Air Force physical fitness tests by females aged <30 years conducted between 2004 and 2014.22

  • CM, average performance on Air Force physical fitness tests by males aged <30 years conducted between 2004 and 2014.22

  • *Adjusted for pretreatment measurements and age when started gender affirming hormones.

  • .