Effect of gender affirming hormones on weight and waist circumference
| Weight (kg) | Transwomen | Transmen |
| Mean (95% CI) | Mean (95% CI) | |
| Time on gender affirming hormones | ||
| Pretreatment | 76.7 (73.3 to 80.2) | 69.5 (66.0 to 72.9) |
| 0–1 years | 75.6 (72.1 to 79.1) | 72.1 (68.6 to 75.5) |
| 1–2 years | 77.1 (73.4 to 80.9) | 71.1 (67.4 to 74.8) |
| 2–2.5 years | 76.7 (70.8 to 82.6) | 70.0 (65.8 to 74.2) |
| β (95% CI) | β (95% CI) | |
| Change in weight per month on hormones* | 0.15 (0.04 to 0.25) | −0.07 (-0.21 to 0.06) |
| Waist circumference (cm) | Mean (95% CI) | Mean (95% CI) |
| Time on gender affirming hormones | ||
| Prereatment | 80.8 (78.7 to 82.8) | 76.7 (74.2 to 79.2) |
| 0–1 years | 79.0 (77.0 to 81.0) | 79.2 (76.5 to 81.8) |
| 1–2 years | 78.9 (76.2 to 81.5) | 78.5 (75.2 to 81.8) |
| 2–2.5 years | 82.0 (76.5 to 87.5) | 78.4 (74.4 to 82.3) |
| β (95% CI) | β (95% CI) | |
| Change in waist per month on hormones* | 0.05 (−0.08 to 0.18) | −0.03 (−0.15 to 0.10) |
All analyses adjusted for variation in the number of measurements per research participant.
*Adjusted for pretreatment measurements and age when started gender affirming hormones.