Moderator | Summary effect | nstudy | Test of moderation | ||||||||
g | LL | UL | t | df | P value | Statistic | df | P value | I2 | ||
Treatment level | |||||||||||
Type of intervention | HTZ=1.86 | 13.8 | 0.183 | 69.64 | |||||||
Aerobic training | 0.35 | 0.02 | 0.69 | 2.35 | 10.06 | 0.041 | 10 | ||||
Resistance training | – | – | – | – | <4 | – | 1 | ||||
Multicomponent | 0.16 | −0.08 | 0.39 | 1.46 | 12.37 | 0.169 | 10 | ||||
Alternative forms | 0.02 | −0.08 | 0.13 | 0.58 | 4.99 | 0.585 | 4 | ||||
Intervention length | HTZ=0.44 | 11.7 | 0.657 | 69.90 | |||||||
Short | 0.14 | −0.03 | 0.31 | 1.72 | 13.33 | 0.108 | 10 | ||||
Medium | 0.21 | −0.11 | 0.54 | 1.44 | 11.20 | 0.177 | 10 | ||||
Long | – | – | – | – | <4 | – | 5 | ||||
Exercise training intensity | HTZ=0.74 | 7.12 | 0.511 | 69.47 | |||||||
Moderate | 0.13 | −0.24 | 0.50 | 0.93 | 4.50 | 0.399 | 5 | ||||
High | – | – | – | – | <4 | – | 3 | ||||
Mixed | 0.24 | −0.02 | 0.51 | 2.16 | 7.83 | 0.064 | 6 | ||||
Unspecified | 0.10 | −0.12 | 0.32 | 1.00 | 12.20 | 0.333 | 11 | ||||
Study level | |||||||||||
Type of dementia | HTZ=3.06 | 3.63 | 0.166 | 69.46 | |||||||
Alzheimer’s disease | 0.56 | 0.03 | 1.09 | 2.49 | 7.35 | 0.040 | 7 | ||||
Vascular dementia | – | – | – | – | <4 | – | 2 | ||||
Multiple types | 0.10 | −0.08 | 0.27 | 1.22 | 11.37 | 0.248 | 10 | ||||
Unspecified | 0.09 | −0.09 | 0.27 | 1.12 | 7.95 | 0.294 | 6 | ||||
Overall risk of bias | HTZ=0.69 | 18.1 | 0.718 | 70.68 | |||||||
Low | 0.14 | −0.003 | 0.28 | 2.32 | 6.82 | 0.054 | 7 | ||||
Some concerns | 0.17 | −0.08 | 0.41 | 1.45 | 12.07 | 0.174 | 10 | ||||
High | 0.28 | −0.07 | 0.63 | 1.79 | 9.59 | 0.156 | 8 | ||||
Comparison group | HTZ=1.85 | 6.73 | 0.230 | 70.34 | |||||||
Usual care | 0.16 | −0.16 | 0.48 | 1.16 | 7.38 | 0.281 | 8 | ||||
Other activities | 0.31 | 0.06 | 0.56 | 2.66 | 14.00 | 0.019 | 11 | ||||
Physically active | – | – | – | – | <4 | – | 4 | ||||
Cognitive training | – | – | – | – | <4 | – | 2 | ||||
Individual level | |||||||||||
Percentage female | HTZ=0.88 | 27.8 | 0.355 | 65.52 | |||||||
Low proportion | 0.22 | −0.01 | 0.45 | 2.05 | 13.9 | 0.060 | 13 | ||||
High proportion | 0.103 | −0.04 | 0.24 | 1.56 | 14.5 | 0.140 | 11 | ||||
Unspecified | – | – | – | – | <4 | – | 1 | ||||
Outcome level | |||||||||||
Cognitive domain | HTZ=0.69 | 14.9 | 0.574 | 69.31 | |||||||
Global cognition | 0.31 | 0.05 | 0.57 | 2.49 | 16.76 | 0.024 | 23 | ||||
Memory | 0.09 | −0.08 | 0.26 | 1.13 | 9.56 | 0.285 | 15 | ||||
Executive function | 0.10 | −0.06 | 0.26 | 1.26 | 18.10 | 0.223 | 9 | ||||
Processing speed | 0.14 | −0.18 | 0.47 | 1.01 | 8.01 | 0.344 | 8 |
df, Degrees of freedom; LL, Lower limit of the 95% confidence interval; UL, Upper limit of the 95% confidence interval.