Demographics | None n=76,428 (76.8%) | Less than 1 times/month n=1454 (1.5%) | 1–3 times/month n=4208 (4.2%) | 1–2 times/week n=8441 (8.5%) | 3–6 times/week* n=8359 (8.4%) | ≥7* times/week n=589 (0.6%) |
Age at randomisation | 62.3 (5.2) | 60.6 (4.8) | 60.8 (4.8) | 61.1 (4.9) | 61.6 (4.9) | 63.2 (5.3) |
Age at follow-up | 71.4 (5.9) | 69.5 (5.7) | 69.8 (5.6) | 70.2 (5.7) | 70.8 (5.6) | 72.6 (6.2) |
No of comorbidities | 1.3 (1.2) | 1.1 (1.2) | 1.1 (1.1) | 1.0 (1.1) | 1.0 (1.1) | 1.2 (1.2) |
BMI (kg/m2) | ||||||
<18.5 18.5–24.9 25–29.9 30–34.9 ≥35 | 2956 (3.9%) 22 804 (30.4%) 31 391 (41.8%) 12 706 (16.9%) 5212 (6.9%) | 56 (3.9%) 488 (34.0%) 635 (44.2%) 193 (13.4%) 64 (4.5%) | 147 (3.6%) 1593 (38.4%) 1710 (41.2%) 522 (12.6%) 174 (4.2%) | 312 (3.8%) 3509 (42.2%) 3299 (39.7%) 927 (11.1%) 264 (3.2%) | 312 (3.8%) 3505 (42.6%) 3235 (39.3%) 936 (11.4%) 236 (2.9%) | 34 (5.8%) 245 (41.9%) 211 (36.1%) 73 (12.5%) 21 (3.6%) |
Sex | ||||||
Men Women | 35 737 (46.8%) 40 691 (53.2%) | 654 (45.0%) 800 (55.0%) | 1938 (46.1%) 2270 (53.9%) | 3847 (45.6%) 4594 (54.4%) | 4604 (55.1%) 3755 (44.9%) | 347 (58.9%) 242 (41.1%) |
Race | ||||||
White Black Hispanic Other | 68 447 (91.4%) 2474 (3.3%) 1073 (1.4%) 2914 (3.9%) | 1292 (91.0%) 49 (3.5%) 26 (1.8%) 53 (3.7%) | 3767 (91.2%) 115 (2.8%) 73 (1.8%) 176 (4.3%) | 7644 (92.5%) 183 (2.2%) 115 (1.4%) 325 (3.9%) | 7495 (91.3%) 158 (1.9%) 175 (2.1%) 385 (4.7%) | 526 (91.3%) 13 (2.3%) 15 (2.6%) 22 (3.8%) |
Smoking | ||||||
Never Former Current | 35 309 (46.9%) 544 (7.4%) 34 386 (45.7%) | 652 (45.5%) 63 (4.4%) 717 (50.0%) | 1935 (46.7%) 183 (4.4%) 2023 (48.9%) | 3813 (45.7%) 308 (3.7%) 4218 (50.6%) | 3649 (44.2%) 323 (3.9%) 4286 (51.9%) | 292 (50.1%) 22 (3.8%) 269 (46.1%) |
Alcohol intake | ||||||
None <0.2 g/day 0.2–1.39 g/day 1.4–10.7 g/day >10.7 g/day | 28 (0.1%) 8703 (25.6%) 8388 (24.6%) 8725 (25.6%) 8209 (24.1%) | 0 (0%) 127 (20%) 143 (22.5%) 181 (28.5%) 184 (29.0%) | 2 (0.1%) 371 (19.9%) 422 (22.6%) 508 (27.3%) 561 (30.1%) | 3 (0.1%) 688 (18.3%) 774 (20.6%) 1102 (29.4%) 1185 (31.6%) | 3 (0.1%) 688 (18.8%) 793 (21.7%) 1009 (27.6%) 1170 (31.9%) | 0 (0%) 69 (24.5%) 69 (25.5%) 61 (22.5%) 72 (26.6%) |
Education | ||||||
<High school High school College >College | 4445 (5.9%) 18 400 (24.6%) 26 250 (35.1%) 25 653 (34.3%) | 19 (1.3%) 176 (12.4%) 444 (31.3%) 779 (54.9%) | 82 (2.0%) 585 (14.2%) 1345 (32.6%) 2114 (51.2%) | 161 (2.0%) 1113 (13.5%) 2633 (31.9%) 4346 (52.7%) | 226 (2.8%) 1258 (15.4%) 2579 (31.5%) 4134 (50.4%) | 39 (6.8%) 105 (18.3%) 188 (32.8%) 242 (42.2%) |
Aerobic MVPA groups | ||||||
None (0 min) Some (1–149 min) Meets (150–300 min) Exceeds (>301 min) | 27 792 (36.7%) 27 871 (36.8%) 15 173 (20.1%) 4847 (6.4%) | 466 (32.2%) 592 (40.9%) 326 (22.5%) 64 (4.4%) | 881 (21.1%) 1923 (46.0%) 1096 (26.2%) 284 (6.8%) | 757 (9.0%) 3603 (48.9%) 3261 (38.9%) 780 (9.3%) | 509 (6.1%) 2416 (29.1%) 3553 (42.8%) 1834 (22.1%) | 76 (13.0%) 144 (24.5%) 171 (29.1%) 196 (33.4%) |
*For regression analysis, these top two categories of 3–6 times/week and ≥7 times/week were combined owing to the small number of deaths in these categories.
BMI, body mass index; MVPA, moderate–vigorous physical activity.