Transgender women (n=15)	Cisgender women (n=13)	Cisgender men (n=14)	Comparison	P
Metabolic aspects
VO2 at rest (ml/min)	328.7 (SD±75.1)	240.1 (SD±31.4)	395.8 (range 229–956)	TW x CW	**
				TW x CM	NS
				CW x CM	**
VO2 AT (ml/min)	1686 (range 1144–1786)	1309 (SD±256.6)	1864 (SD±4417)	TW x CW	NS
				TW x CM	NS
				CW x CM	**
VO2 RCP (ml/min)	2313 (SD±431.0)	1914 (SD±351.2)	2916 (SD±562.9)	TW x CW	*
				TW x CM	**
				CW x CM	****
VO2 Peak (ml/min)	2606 (SD±416.9)	2167 (SD±408.8)	3358 (SD±436.3)	TW x CW	*
				TW x CM	****
				CW x CM	****
VO2 Peak/Wgt. (ml/kg/min)	33.5 (SD±4.7)	35.7 (SD±4.7)	42.0 (range 32.3–49.2)	TW x CW	NS
				TW x CM	**
				CW x CM	**
VO2 Peak/FFM (ml/kg/min)	47.3 (SD±5.1)	53.3 (SD±8.3)	52.4 (SD±5.8)	TW x CW	NS
				TW x CM	NS
				CW x CM	NS
Cardiopulmonary aspects
Peak O2 pulse (ml/Beat)	14.2 (SD±2.1)	11.8 (SD±2.0)	18.5 (range 12.2–22.4)	TW x CW	*
				TW x CM	****
				CW x CM	****
Maximum HR (bpm)	185.7 (SD±11.6)	177.2 (SD±6.1)	181.1 (range 164–189)	TW x CW	*
				TW x CM	NS
				CW x CM	NS
% Maximum HR predicted per age	103.1 (SD±7.3)	96.5 (SD±3.2)	99.2 (SD±3.4)	TW x CW	**
				TW x CM	NS
				CW x CM	NS
VE (BTPS) (L/min)	102.3 (SD±16.2)	87.4 (SD±10.2)	128.8 (SD±18.7)	TW x CW	NS
				TW x CM	**
				CW x CM	****
Strength
				TW x CW	*
Mean strength (kg)	35.3 (SD±5.4)	29.7 (SD±3.6)	48.4 (SD±6.7)	TW x CM	****
				CW x CM	****
				TW x CW	NS
Mean strength/FFM	0.6 (SD±0.1)	0.7 (SD±0.9)	0.7 (SD±0.1)	TW x CM	*
				CW x CM	NS