Table 4

Results from univariable and multivariable logistics regression analysis. Prediction for not achieving the MIC for Combined Sport/Rec and QoL KOOS Scores.

Variablen missingValuen (%) of eventUnivariableArea under ROC-curve (95% CI)Multivariable
OR (95% CI) MIC KOOS Sport and QoLP valueOR (95% CI) MIC KOOS Sport and QoLP value
Age at time of surgery016 to <22


22 to <33


33 to 74
2439 (46.9)


2601 (46.5)


2069 (38.7)
0.86 (0.83 to 0.88)<0.00010.54 (0.53 to 0.55)0.91 (0.88 to 0.94)<0.0001
Sex0Female


Male
3438 (43.8)


3671 (44.4)
1.03 (0.96 to 1.09)0.430.50 (0.50 to 0.51)0.93 (0.87 to 0.99)0.034
BMI449015.1 to <23.1


23.1 to <25.5


25.5 to 45.4
1674 (43.1)


1634 (42.2)


1654 (42.6)
1.00 (0.99 to 1.01)0.900.50 (0.49 to 0.51)
Smoking4305No


Yes
4802 (42.5)


241 (45.9)
1.15 (0.96 to 1.37)0.120.50 (0.50 to 0.51)
Meniscal injury0No


Yes
4098 (45.3)


3011 (42.5)
0.89 (0.84 to 0.95)0.00040.51 (0.51 to 0.52)0.97 (0.90 to 1.04)0.34
Cartilage injury0No


Yes
5219 (44.3)


1890 (43.4)
0.96 (0.90 to 1.03)0.290.50 (0.50 to 0.51)1.17 (1.09 to 1.27)<0.0001
Collateral ligament injury (MCL/LCL)0No


Yes
6829 (44.1)


280 (42.9)
0.95 (0.81 to 1.11)0.530.50 (0.50 to 0.50)
ACL graft528Patellar


Hamstring
396 (51.6)


6445 (43.4)
0.72 (0.62 to 0.83)<0.00010.51 (0.50 to 0.51)0.70 (0.60 to 0.81)<0.0001
Sports-related injury32No


Yes
1073 (45.1)


6025 (43.9)
0.95 (0.87 to 1.04)0.300.50 (0.50 to 0.51)
KOOS pre-operative Sport/Rec and QoL00 to <25


25 to <45


45 to 83.125
1696 (31.7)


2394 (40.9)


3019 (61.3)
1.35 (1.32 to 1.37)<0.00010.64 (0.64 to 0.66)1.34 (1.31 to 1.36)<0.0001
  • Univariable and multivariable logistic regression analysis was used for prediction analyses. All tests were performed with univariable logistic regression, while multivariable logistic regression models were only performed for age at time of surgery, sex, cartilage injury, graft type and KOOS preoperative Sports & QoL. Area under ROC-curve with 95% CI for multivariable model=0.65 (0.64 to 0.66).

  • Bold font indicates significant significance.

  • BMI, body mass index; KOOS, Knee injury and Osteoarthritis Outcome Score; LCL, lateral collateral ligament; MCL, medial collateral ligament; MIC, minimal important change; QoL, quality of life; ROC, receiver operating characteristics; Sport & QoL, combined Sport/Rec and QoL KOOS subscales; Sport/Rec, function in sport and recreation.