Variable | n missing | Value | n (%) of event | Univariable | Area under ROC-curve (95% CI) | Multivariable | ||
OR (95% CI) MIC KOOS Sport and QoL | P value | OR (95% CI) MIC KOOS Sport and QoL | P value | |||||
Age at time of surgery | 0 | 16 to <22 22 to <33 33 to 74 | 2439 (46.9) 2601 (46.5) 2069 (38.7) | 0.86 (0.83 to 0.88) | <0.0001 | 0.54 (0.53 to 0.55) | 0.91 (0.88 to 0.94) | <0.0001 |
Sex | 0 | Female Male | 3438 (43.8) 3671 (44.4) | 1.03 (0.96 to 1.09) | 0.43 | 0.50 (0.50 to 0.51) | 0.93 (0.87 to 0.99) | 0.034 |
BMI | 4490 | 15.1 to <23.1 23.1 to <25.5 25.5 to 45.4 | 1674 (43.1) 1634 (42.2) 1654 (42.6) | 1.00 (0.99 to 1.01) | 0.90 | 0.50 (0.49 to 0.51) | ||
Smoking | 4305 | No Yes | 4802 (42.5) 241 (45.9) | 1.15 (0.96 to 1.37) | 0.12 | 0.50 (0.50 to 0.51) | ||
Meniscal injury | 0 | No Yes | 4098 (45.3) 3011 (42.5) | 0.89 (0.84 to 0.95) | 0.0004 | 0.51 (0.51 to 0.52) | 0.97 (0.90 to 1.04) | 0.34 |
Cartilage injury | 0 | No Yes | 5219 (44.3) 1890 (43.4) | 0.96 (0.90 to 1.03) | 0.29 | 0.50 (0.50 to 0.51) | 1.17 (1.09 to 1.27) | <0.0001 |
Collateral ligament injury (MCL/LCL) | 0 | No Yes | 6829 (44.1) 280 (42.9) | 0.95 (0.81 to 1.11) | 0.53 | 0.50 (0.50 to 0.50) | ||
ACL graft | 528 | Patellar Hamstring | 396 (51.6) 6445 (43.4) | 0.72 (0.62 to 0.83) | <0.0001 | 0.51 (0.50 to 0.51) | 0.70 (0.60 to 0.81) | <0.0001 |
Sports-related injury | 32 | No Yes | 1073 (45.1) 6025 (43.9) | 0.95 (0.87 to 1.04) | 0.30 | 0.50 (0.50 to 0.51) | ||
KOOS pre-operative Sport/Rec and QoL | 0 | 0 to <25 25 to <45 45 to 83.125 | 1696 (31.7) 2394 (40.9) 3019 (61.3) | 1.35 (1.32 to 1.37) | <0.0001 | 0.64 (0.64 to 0.66) | 1.34 (1.31 to 1.36) | <0.0001 |
Univariable and multivariable logistic regression analysis was used for prediction analyses. All tests were performed with univariable logistic regression, while multivariable logistic regression models were only performed for age at time of surgery, sex, cartilage injury, graft type and KOOS preoperative Sports & QoL. Area under ROC-curve with 95% CI for multivariable model=0.65 (0.64 to 0.66).
Bold font indicates significant significance.
BMI, body mass index; KOOS, Knee injury and Osteoarthritis Outcome Score; LCL, lateral collateral ligament; MCL, medial collateral ligament; MIC, minimal important change; QoL, quality of life; ROC, receiver operating characteristics; Sport & QoL, combined Sport/Rec and QoL KOOS subscales; Sport/Rec, function in sport and recreation.