Table 2

Prevalence of osteoporosis and osteopenia at the lumbar spine as measured by dual energy x ray absorptiometry in patients with anorexia nervosa

ReferencePopulation studied (age as mean (SD))Number of subjects studiedPrevalence of either osteoporosis or osteopeniaMean T score (lumbar spine unless stated)
A T score between −1.0 and −2.5 represents osteopenia.
*Two of these three subjects were aged 12 and arguably still gaining bone, so this may represent an overestimate of osteoporosis.
†Different data in abstract (42%) and results sections (50%) for AP lumbar spine by dual energy x ray absorptiometry.
Grinspoon et al11Women with anorexia nervosa aged 24.4 (5.7)13013% osteoporosis−1.4 (mild osteopenia)
50% osteopenia
Young et al33Anorexia nervosa patients aged 18.1 (0.17)186% osteoporosis (1 subject)−1.0 (mild osteopenia/borderline normal)
39% osteopenia
Bachrach et al41Anorexia nervosa patients aged 15.9 (1.5).1817% osteoporosis*−1.5 (osteopenia)
66% had BMD <−2.
56% osteopenia
Seeman et al42Patients with anorexia nervosa aged 21 years (range 12–40)210Not given−1.2 and −1.0 at the femoral neck
Seeman et al43Patients with anorexia nervosa and secondary amenorrhoea aged 24.4 (8.4)37Not given−1.5 (osteopenia)
Grinspoon et al22Adolescents with anorexia nervosa and19<21% with osteoporosis−1.0 (mild osteopenia, borderline normal)
secondary amenorrhoea aged 16.0 (1.7)50% osteopenia†