Oligo/amenorrhoeic premenopausal women: negative effect of oral contraceptives on bone mineral density
| Study design | Reference | No of patients | OC exposure | Measurement of BMD/bone metabolism | Results |
|---|---|---|---|---|---|
| OC, Oral contraceptive; BMD, bone mineral density; EE, ethinyl oestradiol; DXA, dual energy x ray absorptiometry. | |||||
| Case report | Zanker et al71 | 1 amenorrhoeic athlete (followed between age 24.8 to 36. 9 years) | For the first 5 years, used 30 μg EE+150 μg desogestrel | Lumbar spine, proximal femur DXA | 9.8% decrease in lumbar spine BMD and 12.1% decrease in proximal femur BMD during 5 years of OC use |