Table 5

 Systemic factors for lower extremity injuries

DeterminantAuthorInjurySpecification of determinantOutcome (95% CI)
*Not-running injuries and running injuries not involving the lower extremity were included, to establish the outcome.
†Represents adjusted OR or RR.
‡RRs were calculated dividing the number of injured runners by the total number of runner-weeks accumulated (relative incidence ratios).
§RRs were obtained from special subgroups in which information on distances run (miles) and time spent running (hours) was measured.
BMI, body mass index; CI, confidence interval; F, female; M, male; OR, odds ratio; ref, reference; RR, relative risk; y, years.
AgeTaunton et al, 200319Overall injuries*F Age >50 yRR = 1.92 (1.11 to 3.33)†
New injuries*F Age <31 yRR = 0.58 (0.34 to 0.97)†
Satterthwaite et al, 199917Stiffness and/or pain in front thighAge 25–29 y (ref <25 y)OR = 1.42 (0.79 to 2.53)†
Stiffness and/or pain in front thighAge 30–34 y (ref <25 y)OR = 1.83 (1.04 to 3.22)†
Stiffness and/or pain in front thighAge 35–39 y (ref <25 y)OR = 1.34 (0.77 to 2.31)†
Stiffness and/or pain in front thighAge ⩾40 y (ref <25 y)OR = 0.96 (0.56 to 1.63)†
Stiffness and/or pain in calfAge 25–29 y (ref <25 y)OR = 0.60 (0.32 to 1.13)†
Stiffness and/or pain in calfAge 30–34 y (ref <25 y)OR = 0.43 (0.23 to 0.78)†
Stiffness and/or pain in calfAge 35–39 y (ref <25 y)OR = 0.56 (0.31 to 1.01)†
Stiffness and/or pain in calfAge ⩾40 y (ref <25 y)OR = 0.40 (0.23 to 0.73)†
Wen et al, 199821Knee injuriesHigher age‡RR = 2.09 (0.95 to 4.58)†
Overall injuries*Higher age (miles)§RR = 1.08 (0.99 to 1.17)†
Lower age (miles)§RR = 0.39 (0.15 to 0.97)†
Macera et al, 198914Lower extremity injuriesM, higher ageOR = 1.0 (1.0 to 1.0)†
M, higher ageOR = 1.0 (0.9 to 1.0)†
Kretsch et al, 198411Overall injuries*Age 14–20 y (ref ⩾41 y)p<0.025
Nicholl & Williams, 198215Overall injuries*Age 40+ yp<0.05
Macera et al, 199123Lower extremity musculoskeletal problemsM, higher ageOR = 1.0 (1.0 to 1.0)†
F, higher ageOR = 1.0 (0.9 to 1.1)†
Jakobsen et al, 198922Overall injuriesLower agep<0.01
Nicholl & Williams, 198225Overall injuries*Age <40 y (half marathon)OR = 2.12 (1.13 to 3.98)
Age <40 y (marathon)OR = 1.31 (0.76 to 2.25)
SexSatterthwaite et al, 199917Stiffness and/or pain in hamstringMOR = 1.60 (1.04 to 2.47)†
Stiffness and/or pain in hipFOR = 1.88 (1.15 to 3.06)†
Stiffness and/or pain in calfMOR = 1.86 (1.29 to 2.68)†
Bennell et al, 19969Stress fracturesFOR = 3.20 (0.42 to 24.42)
Macera et al, 198914Lower extremity injuriesFOR = 0.89 (0.58 to 1.37)
Nicholl & Williams, 198215Overall injuries*Fp<0.05
Macera et al, 199123Lower extremity musculoskeletal problemsF (marathon)OR = 1.49 (0.53 to 4.25)
F (5 and 10 km)OR = 0.60 (0.32 to 1.10)
Jakobsen et al, 198922Overall injuriesFp>0.05
Nicholl & Williams, 198225Overall injuries*F (half marathon)OR = 1.13 (0.63 to 2.01)
F (marathon)OR = 0.74 (0.34 to 1.61)
HeightWalter et al, 198920New injuries*M 170–179 cm (average) (ref <170)OR = 2.04 (1.15 to 3.46)†
M ⩾180 cm (tallest) (ref <170)OR = 2.30 (1.29 to 3.90)†
F 160–169 cm (average) (ref <160)OR = 1.29 (0.65 to 2.48)†
F ⩾170 cm (tallest) (ref <160)OR = 0.78 (0.32 to 1.97)†
WeightWen et al, 199821Foot injuriesHigher weight‡RR = 0.94 (0.89 to 0.99)†
BMITaunton et al, 200319Overall injury*M, BMI >26RR = 0.41 (0.21 to 0.79)†
Macera et al, 198914Lower extremity injuriesM, BMI (>74th centile)OR = 0.7 (0.5 to 1.2)†
M, BMI (<26th centile)OR = 1.2 (0.7 to 1.9)†
F, BMI (>74th centile)OR = 3.0 (0.5 to 18.8)†
F, BMI (<26th centile)OR = 2.0 (0.6 to 6.6)†
AlignmentLun et al, 200412Overall injuriesLeft subtalar varusCI = 0.2 to 4.2
Wen et al, 199821Overall injuries*Lower leg length difference (h)§RR = 1.96 (1.07 to 3.58)†
Knee injuriesHigher arch index (h)§RR = 0 (0 to 0.37)†
Shin injuriesLower heel valgus (miles)§RR = 0.08 (0.01 to 0.74)†
Foot injuriesHigher heel valgus (miles)§RR = 0.09 (0.01 to 0.81)†
Higher right arch index (h)§RR = 0.11 (0.01 to 0.90)†
Lower right arch index (h)§RR = 0.25 (0.05 to 1.20)†
Higher left tubercle–sulcus angle (miles)§RR = 11.02 (2.00 to 60.86)†
Higher knee varus (miles)§RR = 1.09 (1.03 to 1.15)†
Higher arch index (h)§RR = 0 (0 to 8.21)†
Higher heel valgus (miles)§RR = 0.76 (0.58 to 0.98)†
Higher heel valgus (h) §RR = 0.74 (0.58 to 0.94)†