Table 1 Variables across the menstrual cycle
Follicular phaseOvulation phaseLuteal phaseOverall phase effectBonferroni-adjusted p value
F(df)p ValueF vs OO vs LF vs L
Serum sample and knee joint laxity
    Days of test6.12 (1.42)16.16 (3.02)22.84 (3.29)320.564(2,48)0.000*0.000*0.000*0.000*
    Oestradiol (pg/ml)45.25 (23.93)81.54 (41.17)139.73 (86.81)18.361(2,48)0.000*0.000*0.015*0.000*
    Progesterone (ng/ml)0.99 (0.46)3.34 (2.37)11.66 (7.06)45.119(2,48)0.000*0.000*0.000*0.000*
    Laxity at 89 N (mm)4.78 (1.69)5.20 (1.70)4.62 (1.53)3.526(2,48)0.037*0.2430.015*1.000
Peak knee angle (°)
    Knee abduction5.25 (4.59)5.61 (4.87)5.56 (5.18)0.128(2,44)0.8801.0001.0001.000
    Knee flexion62.77 (6.12)63.49 (6.77)63.77 (8.55)0.497(2,44)0.6121.0001.0001.000
Peak knee moment (Nm)
    External rotation26.13 (14.44)26.43 (15.65)26.65 (15.20)0.007(2,48)0.9931.0001.0001.000
    Internal rotation6.84 (5.96)5.71 (3.10)5.63 (3.14)0.980(2,48)0.3831.0001.0000.708
    Adduction20.16 (18.37)19.24 (20.00)18.95 (20.35)0.073(2,48)0.9301.0001.0001.000
    Abduction88.74 (43.34)88.28 (46.75)88.27 (39.96)0.191(2,48)0.8271.0001.0001.000
    Extension231.99 (49.90)235.38 (64.85)232.42 (60.02)0.112(2,48)0.8851.0001.0001.000
Knee impulse (Nms)
    External rotation2.69 (1.81)2.84 (1.87)2.84 (1.81)0.365(2,48)0.6961.0001.0001.000
    Internal rotation0.08 (0.06)0.08 (0.06)0.06 (0.04)1.103(2,48)0.3401.0000.8520.462
    Adduction0.28 (0.30)0.25 (0.24)0.22 (0.23)0.958(2,48)0.3910.9751.0000.621
    Abduction9.96 (6.70)10.20 (6.64)9.87 (5.66)0.335(2,48)0.7171.0001.0001.000
  • Knee angle data from the first two subjects were not included because of technical problems during data collection. One-way repeated-measures analysis of variance was performed at α = 0.05. Post-hoc test included two-tail paired t test with a Bonferroni adjustment for multiple comparisons (p value was multiplied by the number of comparisons (n = 3)). *p<0.05.

  • F, follicular phase; O, ovulation; L, luteal phase.