Table 2

Sensitivity for the detection of OTS and NFO

MeasureCutoff for OTSOTS (%)NFO (%)
[La]max first exercise test<8 mmol l−18050
[La]max second exercise test<8 mmol l−110067
[Cortisol]rest>175 μgl−18060
[ACTH]rest>40 ng l−18080
[PRL]rest>50 IU l−140100
Cortisol response to second exercise test<200% increase8020
ACTH response to second exercise test<200% increase10080
PRL response to second exercise test<200% increase100100
GH response to second exercise test<1000% increase4040
  • [ACTH]rest,fasted morning adrenocorticotrophic hormone concentration; [Cortisol]rest, fasted morning cortisol concentration; GH, human growth hormone; [La]max, maximal blood lactate concentration; [PRL]rest,fasted morning prolactin concentration.