Table 2

Population-weighted per cent difference in the cardiometabolic risk factor given 1 h/day higher sitting time in US adults ≥20 years (NHANES 2007–2010)

SexRaceSocioeconomic statusMVPA level (min/week)
AllMenWomenCaucasianAAMALowMiddleHigh0<150150–300>300
WC0.30**0.19***0.35*0.24*0.39*0.90***0.61***0.50**0.060.59***0.140.130.01
BMI0.37*0.060.62**0.34*0.561.13***0.64***0.78***−0.010.73**0.180.19−0.07
SBP−0.11−0.13−0.10−0.08−0.240.22−0.27*−0.03−0.09−0.13−0.11−0.150.07
DBP0.050.18−0.10−0.01−0.060.72**−0.080.220.020.100.180.200.07
TG1.03***1.52***0.501.06**0.801.231.20*2.00***0.491.08**1.19−0.162.22**
HDL-C−0.82***−0.97***−0.60*−0.75**−1.17***−0.67−1.17***−1.18***0.50−0.84***−0.38−0.86*−1.13**
Glucose−0.04−0.130.020.02−0.22−0.02−0.060.15−0.220.030.010.03−0.17
Insulin2.41***2.18***2.58***2.36***2.18**2.56**2.37***2.73***1.99***2.77***2.80**1.202.36**
HOMA-IR2.37***2.01**2.58***2.41***1.98*2.50**2.30***2.89***1.77**2.81***2.82*1.232.18*
HOMA-%B2.40***2.27***2.54***2.31***2.60***2.54***2.63***2.30***2.29***2.65***2.55*1.202.54***
2-h glucose†0.65**0.72*0.480.82**0.67*0.720.471.29***0.230.72**1.34*0.120.46
  • ***p<0.001, **p<0.01, *p<0.05.

  • β Coefficients were back-transformed to the geometric mean and converted to percentage difference in the dependent variable per 1 h/day higher sitting time. Each model includes the covariates age, age squared, sex, race/ethnicity, survey cycle, socioeconomic status, educational attainment, marital status, medication use, medical history, family medical history, MVPA min/week, smoking status, energy intake, saturated fat (as a percentage of daily energy intake), sodium intake and alcohol status. For blood pressure, the model also includes potassium, fibre, caffeine and calcium. When stratified, the models exclude the variable of interest (ie, sex, race, socioeconomic status or MVPA level).

  • †Subsample analysis (n=3175).

  • 2 h glucose, 2 h postload plasma glucose; BMI, body mass index; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein-cholesterol; HOMA-IR, homeostatic model assessment of insulin resistance; HOMA-%B, homeostatic model assessment of percentage β cell function; MVPA, moderate-to-vigorous physical activity; SBP, systolic blood pressure; TG, triglycerides; WC, waist circumference.