TableĀ 2

| Type of implementation research objective, implementation question, and research methods

ObjectiveDescriptionImplementation questionResearch methods and data collection approaches
ExploreExplore an idea or phenomenon to make hypotheses or generalisations from specific examplesWhat are the possible factors and agents responsible for good implementation of a health intervention? For enhancing or expanding a health intervention?Qualitative methods: grounded theory, ethnography, phenomenology, case studies and narrative approaches; key informant interviews, focus groups, historical reviews
Quantitative: network analysis, cross sectional surveys
Mixed methods: combining qualitative and quantitative methods
DescribeIdentify and describe the phenomenon and its correlates or possible causesWhat describes the context in which implementation occurs? What describes the main factors influencing implementation in a given context?Quantitative: cross sectional (descriptive) surveys, network analysis
Qualitative methods: ethnography, phenomenology, case studies and narrative approaches; key informant interviews, focus groups, historical reviews
Mixed methods: both qualitative and quantitative inquiry with convergence of data and analyses
InfluenceTest whether an intervention produces an expected outcome
With adequacyWith sufficient confidence that the intervention and outcomes are occurringIs coverage of a health intervention changing among beneficiaries of the intervention?Before-after or time series in intervention recipients only; participatory action research
With plausibilityWith greater confidence that the outcome is due to the interventionIs a health outcome plausibly due to the implemented intervention rather than other causes?Concurrent, non-randomised cluster trials: health intervention implemented in some areas and not in others; before-after or cross sectional study in programme recipients and non-recipients; typical quality improvement studies
With probabilityWith a high (calculated) probability that the outcome is due to the interventionIs a health outcome due to implementation of the intervention?Partially controlled trials: pragmatic and cluster randomised trials; health intervention implemented in some areas and not in others; effectiveness-implementation hybrids
ExplainDevelop or expand a theory to explain the relation between concepts, the reasons for the occurrence of events, and how they occurredHow and why does implementation of the intervention lead to effects on health behaviour, services, or status in all its variations?Mixed methods: both qualitative and quantitative inquiry with convergence of data and analyses
Quantitative: repeated measures of context, actors, depth and breadth of implementation across subunits; network identification; can use designs for confirmatory inferences; effectiveness-implementation hybrids
Qualitative methods: case studies, phenomenological and ethnographic approaches with key informant interviews, focus groups, historical reviews
Participatory action research
PredictUse prior knowledge or theories to forecast future eventsWhat is the likely course of future implementation?Quantitative: agent based modelling; simulation and forecasting modelling; data extrapolation and sensitivity analysis (trend analysis, econometric modelling)
Qualitative: scenario building exercises; Delphi techniques from opinion leaders
  • Adapted from references 8, 14, and 33.