Group | Determinant | Number of studies | Significant relationship LR/HR: n studies | No significant relationship LR/HR: n studies | Best-evidence synthesis | Comments |
---|---|---|---|---|---|---|
Patient characteristics | Older age | 3 | Positive relationship: HR: 237 42 | LR: 156 | Conflicting evidence | |
Higher BMI | 2 | LR: 156 HR: 142 | Limited evidence for no relationship | |||
Intra-articular | Meniscal injury/meniscectomy | 3 | Positive relationship: HR: 141 | LR: 156 HR: 137 | Conflicting evidence | |
Longer time between injury and reconstruction | 3 | LR: 156 HR: 237 42 | Moderate evidence for no relationship | |||
ACL reconstruction (vs non-operative treatment) | 5 | Positive relationship: HR: 231 41 | HR: 319 47 70 | Conflicting evidence | ||
Graft type BPTB (vs HT) | 6 | Positive relationship: HR: 119 | HR: 518 37 38 52 69 | Limited evidence for no relationship | ||
Tunnel placement | 2 | LR: 156 HR: 162 | Limited evidence for no relationship |
ACL, anterior cruciate ligament; BMI, body mass index; BPTB, bone-patellar tendon-bone; HR, high risk of bias studies; HT, hamstring tendon; LR, low risk of bias studies; OA, osteoarthritis.