Table 1

Study and participant characteristics

StudyQuality*Countryn=(ACLD/ ACLR)†Follow-up (years)BMI (kg/m2)Mean age at follow-up (years)Sex (% women)Study designQOL measure(s)
Fithian et al4213America113/96‡7 (3–10)NR45±11, 38±14, 37±14§54, 61, 46§ProspSF-36
Frobell et al1021Sweden29/59524±3¶31±5¶31RCTKOOS, SF-36
Hartwick et al4111Canada17/012 (1–26)2740±847CSACL-QOL
Lohmander et al3215Sweden32/521223 (18–40)31 (26–40)100RetroKOOS, SF-36
Meunier et al3513Sweden36/0**15±1NR36 (29–45)‡¶38ProspKOOS
Michalitsis et al3814Greece32††/05±5263011CSKOOS
Neuman et al3418Sweden71/22‡‡16±1‡26±4‡42±7‡39‡ProspKOOS
Potter et al3312America7/12††7–11NR42±10¶77ProspSF-36
Swirtun and Renström3913Sweden24/226±1NR32±8‡¶48ProspKOOS
Tengman et al3111Sweden37/3323±129±548±638CSKOOS
von Porat et al4014Sweden65/891426±240±60CSKOOS, SF-36
  • All data are reported as range only, mean only, mean±SD, or mean (range).

  • *Quality appraisal scores range from 0 to 21 (worst to best quality).

  • †Number of eligible participants for which QOL outcomes were reported.

  • ‡Included delayed ACL-reconstructed patients.

  • §Data reported separately for ACL-deficient patients grouped by risk level (low, moderate and high) based on baseline knee stability and sports participation.

  • ¶Estimated using mean age from baseline and mean follow-up.

  • **n=42 had a surgical ACL repair, as opposed to ACL reconstruction.

  • ††QOL data provided for a portion of total sample with >5-year follow-up.

  • ‡‡All n=22 were delayed ACL reconstruction.

  • ACLD, anterior cruciate ligament deficient; ACLR, anterior cruciate ligament reconstructed; BMI, body mass index; QOL, quality of life; NR, not reported; Prosp, prospective; RCT, randomised controlled trial; CS, cross-sectional; Retro, retrospective; KOOS, Knee injury and Osteoarthritis Score; SF-36, Short-Form 36.