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Plasma LDH and CK activities after 400 m sprinting by well-trained sprint runners

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Summary

Blood lactate concentration and the activities of plasma LDH and CK were determined in 13 well-trained middle distance runners after a 400-m sprint. It was found that there is a significant relationship between mean velocity in the 400-m sprint and plasma CK activity (r=−0.56,P<0.05), but the mean sprint velocity did not correlate with peak blood lactate concentration (r=−0.09) or plasma LDH activity (r=−0.40). There was a significant negative correlation between mean sprint velocity and H type LDH isozyme activity (r=−0.66,P<0.05), and a significant positive correlation with M type LDH isozyme activity (r=0.66,P<0.05). These results suggest that the magnitude of enzyme efflux from tissue into blood may be depressed by training, and that in well-trained sprinters plasma CK and LDH isozyme activities may be better indicators of physical training and/or physical performance than peak blood lactate or plasma LDH activities.

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Ohkuwa, T., Saito, M. & Miyamura, M. Plasma LDH and CK activities after 400 m sprinting by well-trained sprint runners. Europ. J. Appl. Physiol. 52, 296–299 (1984). https://doi.org/10.1007/BF01015213

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