Elsevier

Atherosclerosis

Volume 85, Issue 1, November 1990, Pages 1-14
Atherosclerosis

Review article
Lipoprotein (a) : structure, properties and possible involvement in thrombogenesis and atherogenesis

https://doi.org/10.1016/0021-9150(90)90177-KGet rights and content

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      As a result, Lp(a) impedes that access of plasminogen to endothelial cell tissue. The induction by Lp(a) of plasminogen activator inhibitor-1 in endothelial cells could also contribute thrombogenesis [41]. It has been reported that a positive history of premature myocardial infarction is predicted by high serum Lp(a) [42,43].

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      Lipoprotein (a) [Lp(a)] consists of apolipoprotein B-100 and apolipoprotein (a) [1], which has several pathogenic roles for atherosclerosis due to the similarity to low-density lipoprotein cholesterol (LDL-C) and thrombosis due to the similarity to plasminogen [2].

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      Lipoprotein(a) [Lp(a)] consists of apolipoprotein(a) and apolipoprotein B-100 and has a similar structure both to low-density lipoprotein (LDL) and to plasminogen [1,2].

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