Elsevier

Metabolism

Volume 34, Issue 6, June 1985, Pages 571-573
Metabolism

The effect of anabolic steroids on lean body mass: The dose response curve☆

https://doi.org/10.1016/0026-0495(85)90196-9Get rights and content

Abstract

Data from human subjects given various amounts of anabolic steroids show that the resultant increment in lean body mass (LBM) has the features of a typical dose response curve. Low doses produce a very modest effect, while large doses result in a progressive augmentation of the LBM. Endogenous testosterone production during male adolescence is accompanied by a sex differential in LBM that is comparable to the LBM increment generated by exogenous steroids given to adults.

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    ☆

    Supported by NIH grants HD-18454 and RR00044, and performed under Contract No. EY-76-C-02-3490 with the US Department of Energy at the University of Rochester Department of Radiation Biology and Biophysics, assigned Report No. UR-3490-2395.

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