Brief report
Hypertrophic cardiomyopathy compatible with successful completion of the marathon

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Cited by (13)

  • Athletic Activity for Patients With Hypertrophic Cardiomyopathy and Other Inherited Cardiovascular Diseases: JACC Focus Seminar 3/4

    2022, Journal of the American College of Cardiology
    Citation Excerpt :

    Although it remains possible that those in this study who exercise the most might have lived the longest because they had mild HCM (and not because of the exercise per se), it is noteworthy that the highest tertile group was exercising ∼3 times greater than the current physical activity recommendations for cardiovascular benefits.36 The heterogeneous morphology and pathophysiology of HCM means that some individuals are capable of participating in vigorous exercise including high-intensity competitive sports37,38; however, none of the studies conducted thus far have been designed or powered to assess the natural history and prognosis of the disease in such individuals. An Italian study reported outcomes in a cohort of 88 athletes with a low risk profile (median age 31 years) following a diagnosis of HCM.

  • Mechanical Dispersion by Strain Echocardiography: A Novel Tool to Diagnose Hypertrophic Cardiomyopathy in Athletes

    2017, Journal of the American Society of Echocardiography
    Citation Excerpt :

    From our data, we cannot exclude that the less altered systolic and diastolic functions observed in athletes with HCM might be due to the beneficial effects of training.20 However, these differences might more likely to be a sign of self-selection (i.e., the athletes with HCM were able to perform competitive sports activity because they had less severe disease).8,9 Even if it might be obvious that athletes with HCM were less severe than sedentary patients with HCM, all were excluded from further intense and competitive sport practice as recommended by current guidelines15,21; nevertheless, they were advised to continue regular recreational sports at low intensity.

  • Sudden death in marathon runners

    2013, Cardiac Electrophysiology Clinics
    Citation Excerpt :

    Most runners (>80%) who have suffered an SCA have not previously reported cardiac symptoms.12 Although HCM may be compatible with marathon running in some cases,26 SCA due to HCM in marathon events has a particularly poor prognosis. In addition to the abnormal myocardial substrate, the additional stresses of exercise, notably adrenergic surges and dehydration, are likely to result in diffuse ischemia and dynamic left ventricular obstruction, which likely hinder resuscitation attempts.

  • Sudden death of the athlete

    1987, Science and Sports
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