Is high concentration of serum lipids a risk factor for Achilles tendon rupture?
Introduction
Although the real incidence of Achilles tendon ruptures (ATR) in the society is not known, it is observed that it has increased in recent years [1], [2], [3]. One of the reasons might be the advance in medicine; especially recent advances in the development of medical diagnostic methods have provided easy recognition of ATR cases [4]. ATR has been found out that it occurs during participation in a sports activity (3–44%) [5], is seen in men more than in women (1.7/1–12/1) [6], occurs usually in the third or fourth decade of life [1], and is generally right-sided [6]. The etiologies of ATR are multifactorial. In the great majority of spontaneous ATR, chronic degenerative changes play main role [7]. Moreover, O blood group [8], inflammatory, autoimmune, genetic, infectious, neurological disorders and some drugs are blamed of the other factors for ATR [6]. In some studies it is claimed that, there might be a relation between ATR and serum lipid profiles [9], [10], [11], [12], [13]. In this study, we aimed to investigate the relation between ATR and serum lipid concentrations.
Section snippets
Material and methods
Serum lipid concentrations of 47 patients with ATR who were admitted to Department of Orthopedics and Traumatology of Gülhane Military Medical Academy (GMMA), between May 1998 and June 2000 were examined. Six of these patients were female. The mean age of the whole group was 25.7 years. The control group consisted of 26 subjects comprised of 20 males and 6 females whose mean age was 32.6 years. Neither the patients nor control subjects had systemic problems with chronic or acute disease, which
Results
There were significant differences between ATR and control group in TC, LDL-C, HDL-C and TG values. Comparison of serum lipid concentrations of two groups is seen in Fig. 1. TC concentration was >5.18 mmol/l in 35 (74.5%) patients, TG concentration was >1.70 mmol/l in 18 (38.3%) patients, LDL-C concentration was >3.36 mmol/l in 33 (70.2%) patients. The concentration of HDL-C was not <0.91 mmol/l in any of the patients. All parameters, including cutoff levels, for ATR and control group, are
Discussion
ATR is easily diagnosed with history, physical exam, some diagnostic tests (e.g., Thompson test) and, in some doubtful situations, ultrasonographic examinations facilitate the diagnose [3], [6], [8], [14].
Revascularization problems and degenerative changes are believed to have an important role in the formation of ATR [7], [15]. Besides, it is claimed that some personal characteristics like blood groups (O and A) and serum uric acid concentrations might be risk factors [9]. In some studies
Acknowledgements
We thank Mark Ervin, M.D., F.S., Landstuhl Regional Medical Center, Germany, for reviewing the manuscript.
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