Elsevier

Clinical Biochemistry

Volume 16, Issue 3, June 1983, Pages 195-199
Clinical Biochemistry

Clinical
Changes in serum myoglobin, total creatine kinase, lactate dehydrogenase and creatine kinase MB levels in runners

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A comparison was made between pre- and post-run serum levels of total creatine kinase (CK), CK-MB isoenzyme, lactate dehydrogenase (LD) and myoglobin (MG) levels in 84 runners in each of three groups; male 5–10 mile run; female 5–10 mile run; and male 15–55 mile run. Levels of CK-MB and MG were quantitated using radioimmunoassay, while total CK and LD were measured using spectrophotometric procedures. Post-run levels of all four markers were significantly higher than the pre-run levels (p < 0.001).

Although levels of enzymes and MG correlated with the sex and distance run, the post-run changes did not correlate with age nor with the smoking status of the runners. Elevation of these markers as a result of vigorous exercise in the absence of myocardial infarction requires cautious interpretation of serum enzyme changes in runners.

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  • Cited by (0)

    1

    Department of Medical Research.

    4

    Departments of Pathology and Microbiology.

    2

    Department of Cardiology.

    3

    Department of Cardiovascular Surgery.

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