Hypertrophic cardiomyopathy is the most common genetic heart disease and is associated with sudden cardiac death and development of heart failure. Risk stratification currently relies only on clinical risk factors, which have low positive predictive value. Myocardial fibrosis, assessed by contrast-enhanced cardiovascular magnetic resonance imaging, may improve risk stratification.
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J. J. Bax has received grants from the following companies: Biotronik, Boston Scientific, Bristol-Myers Squibb Medical Imaging, Edwards Lifesciences, GE Healthcare, Medtronic, St Jude Medical. N. Ajmone Marsan declares no competing interests.
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Ajmone Marsan, N., Bax, J. Myocardial fibrosis assessed by CMR to predict events in HCM. Nat Rev Cardiol 7, 604–606 (2010). https://doi.org/10.1038/nrcardio.2010.137
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DOI: https://doi.org/10.1038/nrcardio.2010.137
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