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Int J Sports Med 1999; 20(7): 444-450
DOI: 10.1055/s-1999-8830
Physiology and Biochemistry
Georg Thieme Verlag Stuttgart ·New York

Serum Leptin During Recovery Following Maximal Incremental and Prolonged Exercise

 M. C. Torjman1 ,  A. Zafeiridis2 ,  A. M. Paolone3 ,  C. Wilkerson1 ,  R. V. Considine4
  • 1 Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
  • 2 Cooper Hospital University Medical Center, Camden, New Jersey, USA
  • 3 Biokinetics Research Laboratory, Temple University, Philadelphia, Pennsylvania, USA
  • 4 Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
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Publication History

Publication Date:
31 December 1999 (online)

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This study investigated the delayed circulating leptin response to maximal and prolonged treadmill exercise. Six healthy untrained males performed three sessions after an overnight fast: control, maximal exercise, and prolonged exercise at 50 % of maximal oxygen consumption. Blood samples were collected prior to exercise, at the end of exercise, and at 60, 120, 180, and 240 min following exercise and control sessions. Blood samples were analyzed for serum leptin, insulin, glucose, free fatty acids, and glycerol. Hemoglobin and hematocrit were measured to correct for plasma volume changes. Resting energy expenditure (REE) and body fat (BF) were also assessed. Immediately at the end of maximal and prolonged exercise, and during the 4 hours of recovery, serum leptin levels did not change significantly compared to their respective baseline values. At 240 min of recovery serum leptin decreased 7 % and 9 % (p > 0.05) from the baseline in the maximal and prolonged sessions, respectively. In the control experiment serum leptin decreased 27 % from the baseline at 240 min of the recovery (p < 0.05). No significant differences were found in leptin values between the control and exercise sessions. Control serum leptin was positively correlated (p < 0.05) to BF (r = 0.88) and glucose (r = 0.96), and negatively correlated to REE (r =- 0.81). In conclusion, maximal or prolonged exercise do not appear to have an influence on circulating serum leptin in the delayed (4 hr) post exercise recovery period.

Key words:

Leptin - exercise - body fat - free fatty acids - glycerol - glucose - insulin

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Ph.D. Marc C. Torjman

Assistant Professor, Department of Anesthesiology Associate Director, Artificial Pancreas Center Jefferson Medical College Thomas Jefferson University

111 South 11th Street

Suite G-8490

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USA

Phone: +1 (215) 955-6161

Fax: +1 (215) 923-5507

Email: marc.torjman@mail.tju.edu

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