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In Vivo Quantification of Blood Flow and Wall Shear Stress in the Human Abdominal Aorta During Lower Limb Exercise

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Abstract

Magnetic resonance (MR) imaging techniques and a custom MR-compatible exercise bicycle were used to measure, in vivo, the effects of exercise on hemodynamic conditions in the abdominal aorta of eleven young, healthy subjects. Heart rate increased from 73±6.2 beats/min at rest to 110±8.8 beats/min during exercise (p < 0.0001). The total blood flow through the abdominal aorta increased from 2.9±0.6 L/min at rest to 7.2±1.4 L/min during exercise (p < 0.0005) while blood flow to the digestive and renal circulations decreased from 2.1±0.5 L/min at rest to 1.6±0.7 L/min during exercise (p < 0.01). Infrarenal blood flow increased from 0.9±0.4 L/min at rest to 5.6±1.1 L/min during exercise (p < 0.0005). Wall shear stress increased in the supraceliac aorta from 3.5±0.8 dyn/cm2 at rest to 6.2±0.5 dyn/cm2 during exercise (p < 0.0005) and increased in the infrarenal aorta from 1.3±0.8 dyn/cm2 at rest to 5.2±1.3 dyn/cm2 during exercise (p < 0.0005). © 2002 Biomedical Engineering Society.

PAC2002: 8719Uv, 8761-c

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Authors and Affiliations

  1. Department of Surgery, Stanford University, Stanford, CA

    Charles A. Taylor

  2. Department of Mechanical Engineering, Stanford University, Stanford, CA

    Charles A. Taylor, Christopher P. Cheng, Leandro A. Espinosa, Beverly T. Tang & David Parker

  3. Department of Radiology, Stanford University, Stanford, CA

    Robert J. Herfkens

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Taylor, C.A., Cheng, C.P., Espinosa, L.A. et al. In Vivo Quantification of Blood Flow and Wall Shear Stress in the Human Abdominal Aorta During Lower Limb Exercise. Annals of Biomedical Engineering 30, 402–408 (2002). https://doi.org/10.1114/1.1476016

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