Effects of Physical Training on the Recovery of the Autonomic Nervous Activity During Exercise After Coronary Artery Bypass Grafting - Effects of Physical Training After CABG -

Junichiro Takeyama; Haruki Itoh; Makoto Kato; Akira Koike; Keiichi Aoki; Long Tai Fu; Hiroshi Watanabe; Masatoshi Nagayama; Takashi Katagiri

doi:10.1253/jcj.64.809

Clinical Investigations

Effects of Physical Training on the Recovery of the Autonomic Nervous Activity During Exercise After Coronary Artery Bypass Grafting

- Effects of Physical Training After CABG -

Junichiro Takeyama, Haruki Itoh, Makoto Kato, Akira Koike, Keiichi Aoki, Long Tai Fu, Hiroshi Watanabe, Masatoshi Nagayama, Takashi Katagiri

Author information

Junichiro Takeyama
Third Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan
Haruki Itoh
Cardiovascular Institute Hospital, Showa University School of Medicine, Tokyo, Japan
Makoto Kato
Cardiovascular Institute Hospital, Showa University School of Medicine, Tokyo, Japan
Akira Koike
Cardiovascular Institute Hospital, Showa University School of Medicine, Tokyo, Japan
Keiichi Aoki
Cardiovascular Institute Hospital, Showa University School of Medicine, Tokyo, Japan
Long Tai Fu
Cardiovascular Institute Hospital, Showa University School of Medicine, Tokyo, Japan
Hiroshi Watanabe
Cardiovascular Institute Hospital, Showa University School of Medicine, Tokyo, Japan
Masatoshi Nagayama
Third Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan
Takashi Katagiri
Third Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan

Keywords: Aerobic exercise training, Coronary artery bypass grafting, Heart rate variability, Norepinephrine

JOURNAL FREE ACCESS

2000 Volume 64 Issue 11 Pages 809-813

DOI https://doi.org/10.1253/jcj.64.809

Details

Abstract

Analysis of heart rate variability (HRV) can identify patients at risk of sudden cardiac death after myocardial infarction. The present study examined the effect of 2 weeks of supervised aerobic exercise training on the recovery of the autonomic nervous activity, exercise capacity, and cardiac output (CO) after coronary artery bypass grafting (CABG). Twenty-eight patients were randomly divided into the training group or the control group and performed exercise tests at 1 week, 3 weeks, 3 months, 6 months and 1 year after CABG. The HRV was measured, and the high-frequency component of HRV was used as an index of parasympathetic nerve activity (PNA); the plasma norepinephrine concentration (NE) was used as an index of sympathetic nervous activity. Cardiac output was also measured. In the training group, peak VO₂, peak CO and PNA during exercise had improved at 3 weeks, but there was no improvement in these indices in the control group. NE decreased 1 week after CABG in both groups. These results indicate that physical training soon after CABG improves not only the exercise capacity, but also PNA.

Corresponding author

Register with J-STAGE for free!