A growing number of children and adolescents are involved in resistance training in schools, fitness centers, and sports training facilities. In addition to increasing muscular strength and power, regular participation in a pediatric resistance training program may have a favorable influence on body composition, bone health, and reduction of sports-related injuries. Resistance training targeted to improve low fitness levels, poor trunk strength, and deficits in movement mechanics can offer observable health and fitness benefits to young athletes. However, pediatric resistance training programs need to be well-designed and supervised by qualified professionals who understand the physical and psychosocial uniqueness of children and adolescents. The sensible integration of different training methods along with the periodic manipulation of programs design variables over time will keep the training stimulus effective, challenging, and enjoyable for the participants.