Athletes travel across multiple time zones in order to engage in national or international competition. It has often been assumed that rapid transmeridian translocation has a negative impact on athletic performance. However, the available studies are characterised by major methodological problems. Consequently, no compelling evidence exists demonstrating that air travel adversely influences athletic performance. Evidence suggests that distance and sprint running performance, as well as dynamic muscular strength and endurance of the elbow flexors, is impaired following west-east travel across 6 times zones in untrained individuals. However, there is no evidence that these findings for untrained subjects generalise to athletes. Both physiological and psychological mechanisms might account for potential effects of travel on athletic performance, but little is known about these potential mechanisms with regards to athletic performance. Systematic research is needed if the relationship between air travel and athletic performance is to be elucidated.