Coarctation of the abdominal aorta: pathophysiologic and therapeutic considerations

Ann Surg. 1979 Jun;189(6):746-57. doi: 10.1097/00000658-197906000-00011.

Abstract

Coarctation of the aorta is the most frequent cause of hypertension in infants and children. Ninety-eight per cent of coarctations occur in the descending aorta near the ligamentum arteriosus. Five patients are presented with the relatively rare problem of coarctation of the abdominal aorta. The anatomic,pathophysiologic and clinical aspects in these patients cover a range of variants. Clinical and laboratory studies of the genesis of hypertension in coarctation are reviewed in chronologic outline. An experimental model of abdominal coarctation with hypertensive and renin-angiotensin II correlations suggests but does not prove a renal mechanism for the hypertension. The same conclusion must be drawn from study of the clinical cases.

Publication types

  • Case Reports
  • Historical Article

MeSH terms

  • Adolescent
  • Aorta, Abdominal / diagnostic imaging
  • Aortic Coarctation / complications
  • Aortic Coarctation / diagnostic imaging
  • Aortic Coarctation / history
  • Aortic Coarctation / physiopathology
  • Aortic Coarctation / surgery*
  • Child
  • Child, Preschool
  • History, 20th Century
  • Humans
  • Hypertension / etiology
  • Hypertension / history
  • Infant
  • Male
  • Radiography
  • Renal Artery Obstruction / diagnostic imaging
  • Renal Artery Obstruction / etiology