abstract Schistosomiasis, a neglected tropical disease of poverty ranks second among the
most widespread parasitic disease in various nations in sub-Saharan Africa. Neglected …

Heat shock proteins (HSPs) play cytoprotective activities under pathological conditions
through the initiation of protein folding, repair, refolding of misfolded peptides, and possible …

Crops aimed at feeding an exponentially growing population are often exposed to a variety
of harsh environmental factors. Although plants have evolved ways of adjusting their …

Modulating disease-relevant protein-protein interactions (PPIs) using small-molecule
inhibitors is a quite indispensable diagnostic and therapeutic strategy in averting …

Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases
worldwide, as it affects up to 30% of adults in Western countries. Moreover, NAFLD is also …

Excessive free radical generation, especially reactive oxygen species (ROS) leading to
oxidative stress in the biological system, has been implicated in the pathogenesis and …

Protein–protein interactions (PPI) are vital in modulating biochemical pathways in many
biological processes. Inhibiting PPI is a tremendously important diagnostic and therapeutic …

In the next century, global warming, due to changes in climatic factors, is expected to have
an enormous influence on the interactions between pathogens and their hosts. Over the …

Isoorientin is a natural C-glucosyl flavone that is generating a lot of interest due to its
multiple pharmacological activities. Increasing experimental data have shown that the robust …

Presently, many studies have focused on exploring in silico approaches in the identification
and development of alternative therapy for the treatment and management of cancer. Solute …