Inflammatory response represents one of the first immune processes following injury. It is
characterized by the production of various molecules that initiate the recruitment of immune …

The chemokine CXCL12/stromal cell-derived factor 1 alpha has first been described in the
immune system where it functions include chemotaxis for lymphocytes and macrophages …

The chemokine SDF-1α and its cognate receptor CXCR4 are expressed in several neuronal
populations. This review focuses on our current knowledge about the actions of this …

Background Genetic and environmental factors are critical elements influencing the etiology
of major depression. It is now accepted that neuroinflammatory processes play a major role …

Current antidepressant treatments are inadequate for many individuals, and when they are
effective, they require several weeks of administration before a therapeutic effect can be …

The action of ethosuximide (ETX) on Na+, K+, and Ca2+ currents and on tonic and burst-
firing patterns was investigated in rat and cat thalamic neurons in vitro by using patch and …

Regulation of neuroinflammation by glial cells plays a major role in the pathophysiology of
major depression. While astrocyte involvement has been well described, the role of …

Chemokines are small secreted proteins that chemoattract and activate immune and non-
immune cells. Their role in the immune system is well-known, and it has recently been …

Accumulating evidence show that chemokines can modulate the activity of neurons through
various mechanisms. Recently, we demonstrated that CCR2, the main receptor for the …

Ependymal cell cilia help move cerebrospinal fluid through the cerebral ventricles, but the
regulation of their beat frequency remains unclear. Using in vitro, high-speed video …